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Rabbit Anti-NEGR1 Polyclonal Antibody#abs134542

Please be advised that the price provided is for your reference only. For detailed pricing information, we kindly ask you to get in touch with our seller, Vecent. Western blot analysis of extracts from COLO cells, using NEGR1 antibody. This product is for research use only, not for use in...

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Description

Catalog-specification	Delivery time	USD price
abs134542-100ug	1-2 Weeks	301.0
abs134542-50ug	1-2 Weeks	201.0

Please be advised that the price provided is for your reference only. For detailed pricing information, we kindly ask you to get in touch with our seller, Vecent.

Overview
catalog	abs134542
Other names	IgLON family member 4, also known as IgLON4 or KILON, is a member of the IgLON family. It is encoded by the DMML2433 gene or MGC46680, and its alternative names include Neurotractin, Neuronal growth regulator 1, Ntra, PRO4993, and UNQ2433. This protein is a part of the IgLON family, which plays a role in neuronal growth regulation. IgLON4 is specifically involved in the regulation of neuronal growth and development, making it a crucial player in the intricate network of the nervous system. The precise functions of IgLON4 are still being elucidated, but research suggests that it contributes to the formation and development of neural connections. It is believed to be expressed mainly in the brain, particularly in regions that are critical for cognitive functions and memory. By understanding the role of IgLON4 and its interaction with other members of the IgLON family, scientists aim to gain insights into the mechanisms underlying brain development and function. Such knowledge could potentially open up new avenues for therapeutic interventions in neurodevelopmental and neurodegenerative disorders. Overall, IgLON4, with its alternative names like Neurotractin and Neuronal growth regulator 1, represents an intriguing protein with significant implications for our understanding of the complex dynamics of the nervous system.
Source	Rabbit
Specificity	The NEGR1 Antibody is designed to specifically detect total NEGR1 levels in the endogenous state. To produce an equivalent statement, the content could be rephrased as: The total NEGR1 levels present in the endogenous state can be detected using the NEGR1 Antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Horse
Antigen	NEGR1
Application	To use this antibody in Western blotting, dilute it in a range of 1:500 to 1:1000. For immunofluorescence or immunocytochemistry applications, a dilution range of 1:100 to 1:500 is recommended. When using this antibody in an ELISA assay with peptide substrates, a dilution range of 1:20000 to 1:40000 is suggested. Please note that these dilution ranges have been optimized for the best results and could be adjusted based on individual experiments.
Immunogen	A synthesized peptide.
MW	35 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to conduct peptide affinity chromatography for the purification of the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is advised to keep it stored at a temperature of -20 °C for a period of one year. To prevent any damage to the product, it is recommended to avoid any instances of repeated freeze and thaw cycles.
Storage buffer	The Rabbit IgG solution is formulated in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl and 0.02% sodium azide. It also contains 50% glycerol to maintain stability during storage at -20 °C. The product is guaranteed stable for 12 months from the date it is received.
Target
Background	May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity).
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	Q7Z3B1