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Rabbit Anti-AMPD2 Polyclonal Antibody#abs140845

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Description

Catalog-specification	Delivery time	USD price
abs140845-100ug	1-2 Weeks	301.0
abs140845-50ug	1-2 Weeks	201.0

Overview
catalog	abs140845
Other names	Adenosine monophosphate deaminase 2 (isoform L), also known as AMP deaminase 2, is a protein that plays a crucial role in the energy metabolism process by catalyzing the deamination of adenosine monophosphate (AMP) to inosine monophosphate (IMP) and ammonia. This process generates energy for muscle contraction and maintenance. AMP deaminase 2 is encoded by the AMPD2 gene and is expressed mainly in skeletal muscles. Mutations in this gene have been associated with various neuromuscular disorders, including hereditary spastic paraplegia (SPG63). The RP5-1160K1.5 gene is a non-coding RNA gene that is located near the AMPD2 gene on chromosome 1. Research is ongoing to determine the function of this gene.
Source	Rabbit
Specificity	The AMPD2 Antibody is designed to specifically recognize and measure the levels of total AMPD2 present in an organism. By detecting the endogenous levels of AMPD2, this antibody allows for the accurate assessment of AMPD2 expression. It is important to note that this content has been generated by the language model and may differ from the original text in terms of wording and structure.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
Antigen	AMPD2
Application	The dilution ratio for Western Blotting (WB) ranges from 1:500 to 1:1000. For Immunofluorescence (IF) or Immunocytochemistry (ICC), the recommended dilution is 1:100 to 1:500. In the case of ELISA using peptide antigens, the suggested dilution lies between 1:20000 and 1:40000.
Immunogen	A synthesized peptide.
MW	100 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. A highly similar content can be generated by rephrasing the original text to highlight the same information in a different way.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the integrity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing, as this can have a negative impact on its quality and efficacy. Taking proper storage precautions is crucial for ensuring that the product remains effective and usable for its intended purpose.
Storage buffer	The rabbit IgG is stored in a solution containing phosphate buffered saline at pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol, and should be kept at a temperature of -20 °C. This solution is stable for 12 months from the date of receipt, making it an ideal storage solution for researchers and scientists who work with rabbit IgG. By following these guidelines for storage and handling, researchers can ensure that their samples remain stable and effective for use in future studies and experiments.
Target
Background	AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.
Tissue specificity	Highly expressed in cerebellum.
Celluar localization	Cytosol;
UniPort	Q01433