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Rabbit Anti-NCKIPSD Polyclonal Antibody#abs139419

Please note that the price provided is for reference purposes only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis NCKIPSD using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs139419-100ug	1-2 Weeks	301.0
abs139419-50ug	1-2 Weeks	201.0

Please note that the price provided is for reference purposes only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs139419
Other names	Here are some options to rearrange and generate new content based on the initial text: - The protein known as DIP-1, or dia-interacting protein 1, has multiple aliases, including 54 kDa VacA-interacting protein, 54 kDa vimentin-interacting protein, and AF3p21. It also interacts with Nck, a 90 kDa SH3 protein, and is sometimes referred to as NCK-interacting protein with SH3 domain or SH3 adapter protein SPIN90. Another name for it is VIP54. It is a key protein involved in regulating actin dynamics and cell motility. - WISH, or Wiskott-Aldrich syndrome protein-interacting protein, is also known as WASP-interacting SH3-domain protein or WASLBP. It binds to and regulates the activity of the actin regulator WASP, but it is also involved in other cellular processes. Additionally, it interacts with Nck and is sometimes called SH3 protein interacting with Nck 90 kDa or Nckipsd. Another name for it is SPIN90. It has important roles in cell migration, adhesion, and spreading. - The 54 kDa protein that interacts with VacA and vimentin is also called AF3p21 or DIP. It binds to Dia, or diaphanous protein, and is therefore known as dia-interacting protein 1 or DIP-1. It also interacts with Nck through its SH3 domain, leading to the names NCK-interacting protein with SH3 domain or SH3 adapter protein SPIN90. Additionally, it is sometimes referred to as VIP54. This protein plays a role in regulating actin dynamics and cell motility by modulating the activity of Dia and other actin regulators.
Source	Rabbit
Specificity	The NCKIPSD Antibody is capable of detecting total NCKIPSD at levels that occur naturally within the organism. This means that the antibodies are able to recognize and bind to the protein in a precise and specific manner, allowing for accurate measurement of its expression levels.
Species Reactivity	Human;Mouse
Predictive reaction species	Zebrafish;Rabbit;Pig;Dog;Horse;Sheep;Bovine
Antigen	NCKIPSD
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human NCKIPSD.
MW	79 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the purification of the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.
Tissue specificity	Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen.
Celluar localization	Cytoskeleton;Cytosol;Nucleus;
UniPort	Q9NZQ3