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Rabbit Anti-MYO5A Polyclonal Antibody#abs134502

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Description

Catalog-specification	Delivery time	USD price
abs134502-100ug	1-2 Weeks	301.0
abs134502-50ug	1-2 Weeks	201.0

Overview
catalog	abs134502
Other names	There are a variety of names for the non-muscle myosin heavy chain, including dilute myosin heavy chain, GS1, MYH12, MYO5, and Myo5a. It is also commonly referred to as Myosin V or Myosin VA. This protein is responsible for a range of cellular processes including transport, cytokinesis, and cell migration. The Myosin heavy polypeptide kinase plays a role in regulating the activity of the myosin heavy chain. Interestingly, MYO5A_HUMAN, also known as Myosin-12 or MYR12, is considered an unconventional myosin-Va due to its unique structure and function in comparison to other myosin subtype proteins. It is important to note that the different names used to describe the non-muscle myosin heavy chain stem from different research methods and observations. Nonetheless, they all refer to the same underlying molecular structure and biological functions.
Source	Rabbit
Specificity	The total MYO5A levels in the body can be effectively detected using the MYO5A Antibody, which specifically targets the endogenous MYO5A protein.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	MYO5A
Application	The dilution ratio for western blotting (WB) ranges from 1:500 to 1:1000. For immunofluorescence (IF) or immunocytochemistry (ICC), the dilution ratio is typically between 1:100 and 1:500. In the case of ELISA with a peptide substrate, the recommended dilution range is 1:20000 to 1:40000. It is important to note that these dilution ratios are crucial in obtaining accurate and reliable results in these experimental techniques.
Immunogen	A synthesized peptide.
MW	220 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C. It can be kept at this temperature for up to one year without any adverse effects. However, it is essential to avoid subjecting the product to repeated freeze/thaw cycles, as this may compromise its stability and effectiveness. Therefore, it is imperative to follow these storage guidelines to ensure that the product remains effective and potent over the desired period.
Storage buffer	The provided information is about Rabbit IgG, which is stored in phosphate buffered saline with a pH of 7.4. It contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store it at -20 °C, and it remains stable for 12 months from the date of receipt. Please note that the request is to generate significantly different content, not adhering to ChapGPT-like conversation.
Target
Background	Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.
Tissue specificity	Detected in melanocytes.
Celluar localization	Cytoskeleton;Cytosol;Extracellular region or secreted;Golgi apparatus;
UniPort	Q9Y4I1