Rabbit Anti-MPRA Polyclonal Antibody#abs135289

Rabbit Anti-MPRA Polyclonal Antibody#abs135289

Please note that the price mentioned is only for your reference, and for detailed pricing information, please get in touch with our seller Vecent. It is important to understand that the content generated here is based on the original text and rearranged to convey the same message. As an AI...

Description

Catalog-specificationDelivery timeUSD price

abs135289-100ug

1-2 Weeks

301.0

abs135289-50ug

1-2 Weeks

201.0

Please note that the price mentioned is only for your reference, and for detailed pricing information, please get in touch with our seller Vecent. It is important to understand that the content generated here is based on the original text and rearranged to convey the same message. As an AI language model, I generate text differently compared to ChapGPT, so please avoid initiating conversations in a way that resembles its functionality.


Overview

catalog

abs135289
Other namesThe alpha isoform of the membrane progestin receptor is also known as mPR alpha, MRPA, or mSR. Other names for this receptor include PAQR7, PGLP, and Progestin and adipoQ receptor family member VII.
SourceRabbit
SpecificityThe detection of endogenous levels of total MPRA is achieved using the MPRA Antibody. By rearranging the information from the original text, a highly similar content can be generated.
Species ReactivityHuman;Mouse
AntigenMPRA
ApplicationFor Western blotting, a dilution of 1:500 to 1:1000 is recommended, while for immunofluorescence and immunocytochemistry, a dilution range of 1:100 to 1:500 is suggested. When performing ELISA with peptide antigens, it is recommended to use a dilution of 1:20000 to 1:40000. Please note that these dilutions are based on the original text information and should be adjusted for specific experimental conditions.
ImmunogenA synthesized peptide.
MW40 KD
Properties

Concentration

1mg/ml

purificationUsing SulfoLink™ Coupling Resin, peptide affinity chromatography was utilized to purify the antiserum. An efficient method, this process resulted in a highly purified and concentrated antiserum.
ClonalityPolyclonal Antibody
Stability & StoragePlease ensure that the product is stored at a temperature of -20 °C for one year to maintain its quality. It is important to avoid subjecting the product to repeated freeze/thaw cycles during storage.
Storage bufferThe recommended storage conditions for Rabbit IgG are at -20 °C in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the product is guaranteed for a period of 12 months from the date of receipt.

Target

Background

The G protein-coupled receptor for progesterone (P4) is located on the plasma membrane and has been extensively studied (PubMed:23763432). It appears to exert its effects through a pathway mediated by G(i) proteins (PubMed:23763432). One of its important roles is believed to be in the maturation of oocytes (PubMed:12601167). Additionally, this receptor plays a role in the neurosteroid-mediated inhibition of apoptosis (PubMed:23161870). It is worth noting that this receptor also binds other hormones such as dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone, and allopregnanolone (PubMed:23161870).

Tissue specificityExpressed in a wide range of tissues including ovary, testis, placenta, uterus and bladder.
Celluar localizationPlasma Membrane;
UniPortQ86WK9


Western blot analysis of extracts from 293 cells and COLO cells, using MPRA antibody.

This product is for research use only, not for use in diagnostic prodecures or in human.


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