Rabbit Anti-MAP3K6 Polyclonal Antibody #abs130357

abs130357-50ug

1-2 Weeks

201

abs130357-100ug

1-2 Weeks

301

Description

This gene encodes a member of the STE11 protein kinase family. It has been reported to activate the JNK pathway, while having no effect on either the ERK or p38 pathways. Interestingly, two alternative splicing variants of this gene have been identified, each encoding distinct isoforms. This suggests that this gene and its encoded protein may have diverse roles in various cellular processes.

Other names

ASK2, also known as apoptosis signal-regulating kinase 2 or MAP3K6, is an important enzyme involved in apoptosis regulation. It plays a crucial role in initiating the apoptotic signaling cascade. ASK2, classified under EC 2.7.11.25, is a member of the mitogen-activated protein kinase kinase kinase (MAPKKK) family. It is also referred to as M3K6_HUMAN, MAPKKK6, or MEKK6 in various contexts. Other aliases for ASK2 include MGC125653, MGC20114, and Mitogen-activated protein kinase kinase kinase 6. This multifunctional kinase is instrumental in numerous cellular processes, particularly those related to apoptosis. By rearranging the provided information, we can provide a similar content description of ASK2.

Source

Rabbit

Specificity

The detection of endogenous levels of MAP3K6 can be achieved using the MAP3K6 Antibody.

Species Reactivity

Human;Mouse

Application

IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Immunogen

A synthesized peptide derived from human MAP3K6

Properties

Concentration

1mg/ml

Purification

Immunogen affinity purified

Clonality

Polyclonal Antibody

Stability & Storage

For an entire year, keep the item stored at -20 °C to maintain its efficacy. Be sure to prevent the item from undergoing frequent cycles of freezing and thawing. It's crucial to follow these storage instructions to ensure maximum effectiveness of the product.

Storage buffer

Phosphate buffered saline containing Rabbit IgG, with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol should be stored at -20 °C. This formulation remains stable for a period of 12 months from the date of receipt. It is important to note that the generated content should be significantly different from the original text, as per the requested instructions.

Target

Background

A key player in the protein kinase signal transduction cascade, this component selectively triggers the activation of JNK, while leaving ERK and p38 kinase pathways unaffected.

UniPort

O95382