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Rabbit Anti-MAEA Polyclonal Antibody#abs133634

Please note that the price mentioned is only for your reference. For detailed pricing information, we request you to kindly get in touch with our seller Vecent. Western blot analysis of extracts from COLO205 cells, using MAEA antibody. This product is for research use only, not for use in...

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Description

Catalog-specification	Delivery time	USD price
abs133634-100ug	1-2 Weeks	301.0
abs133634-50ug	1-2 Weeks	201.0

Please note that the price mentioned is only for your reference. For detailed pricing information, we request you to kindly get in touch with our seller Vecent.

Overview
catalog	abs133634
Other names	The 1110030D19Rik protein, also known as cell proliferation inducing gene 5 protein or PIG5, plays a crucial role in the growth and multiplication of cells. It is a member of the GID complex and is homologous to FYV10. Other names for this protein include EMLP, EMP, HLC-10, and GID9. MAEA, or macrophage erythroblast attacher, is another name for this protein as it is known to facilitate the attachment of macrophages to erythroblasts. It is also referred to as lung cancer related protein 10 or human lung cancer oncogene 10 protein due to its association with cancer. MGC93683 is another designation for this protein. In summary, the 1110030D19Rik or PIG5 protein is critical for cell growth and proliferation and has multiple aliases due to its association with various physiological processes.
Source	Rabbit
Specificity	The MAEA Antibody has the ability to recognize and bind to all forms of MAEA present in the body. This means it can accurately detect the natural levels of total MAEA.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Chicken;Pig;Dog;Sheep;Bovine;Horse
Antigen	MAEA
Application	The recommended dilution for WB is 1:500~1:1000, for IF/ICC it is 1:100-1:500 and for ELISA (peptide) it is 1:20000-1:40000. It is important to note that these dilutions are based on the original text information and should be followed in order to obtain accurate and reliable results. Dilution factors outside of these ranges may result in decreased sensitivity and specificity of the assay. Therefore, it is crucial to use appropriate dilutions for all experiments to ensure accurate and reproducible data.
Immunogen	A synthesized peptide.
MW	45 KD
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin to perform peptide affinity chromatography for the purification of the antiserum. Hence, I have rearranged the provided content to generate a new statement based on the original information.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimal storage conditions, it is recommended to store at a temperature of -20 °C for a period of one year. Avoid the occurrence of repeated freeze/thaw cycles which may negatively impact the quality of the product and its effectiveness. It is essential to adhere to these guidelines in order to safeguard the integrity of the product and ensure the optimal performance of the same.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.
Tissue specificity	Ubiquitous.
Celluar localization	Cytoskeleton;Nucleus;Plasma Membrane;
UniPort	Q7L5Y9