Rabbit Anti-LHB Polyclonal Antibody#abs136660

Rabbit Anti-LHB Polyclonal Antibody#abs136660

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Description

Catalog-specificationDelivery timeUSD price

abs136660-100ug

1-2 Weeks

301.0

abs136660-50ug

1-2 Weeks

201.0

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Overview

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abs136660

Description

The beta subunit of luteinizing hormone (LH) is encoded by a gene belonging to the glycoprotein hormone beta chain family. Glycoprotein hormones consist of a common alpha subunit and a unique beta subunit that determines their function. LH is expressed in the pituitary gland and plays a crucial role in stimulating the production of steroids in the testes and ovaries, which promote ovulation and spermatogenesis.
The genes for the beta chain of chorionic gonadotropin and for luteinizing hormone are adjacent on chromosome 19q13.3. Mutations in this gene can result in hypogonadism, a condition characterized by infertility and pseudohermaphroditism.

Other namesThe beta polypeptide 4 of chorionic gonadotropin, also known as CGB4, is an essential protein that plays a crucial role in reproductive health. It is also referred to as hLHB, LSH beta, Luteinizing hormone subunit beta, and Lutropin subunit beta. CGB4, along with luteinizing hormone beta polypeptide (LHB), is responsible for controlling the menstrual cycle and stimulating the production of other hormones that are crucial for fertility. This protein is a part of the gonadotropin family and is mainly produced by the pituitary gland and placenta. The LSH-B protein binds to specific receptors present on the surface of ovarian cells, triggering the synthesis of sex hormones. The regulation of CGB4 is vital for reproductive health and must be closely monitored. Any disruption in its production or function can lead to infertility or other reproductive disorders.
SourceRabbit
SpecificityThe LHB Antibody is effective in detecting total levels of endogenous LHB. If you are looking for a reliable and accurate method to measure LHB in a sample, this antibody would be a great choice. With its ability to recognize all forms of LHB, you can trust that your results will be consistent and dependable. Whether you are conducting research on reproductive health or studying the effects of different treatments, the LHB Antibody is an essential tool for any laboratory. Don't settle for anything less than the best when it comes to measuring LHB – choose the LHB Antibody.
Species ReactivityHuman;Mouse;Rat
AntigenLHB
ApplicationWB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
ImmunogenA synthetic peptide of human LHB.
MW15kD
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage bufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Target

Background

Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

Tissue specificityPituitary gland.
Celluar localizationExtracellular region or secreted;Golgi apparatus;
UniPortP01229


Western blot analysis of extracts of Mousepituitary cell line, using LHB antibody.


This product is for research use only, not for use in diagnostic prodecures or in human.


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