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Rabbit Anti-LAMTOR3 Polyclonal Antibody#abs137115

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Description

Catalog-specification	Delivery time	USD price
abs137115-100ug	1-2 Weeks	301.0
abs137115-50ug	1-2 Weeks	201.0

Overview
catalog	abs137115
Other names	LTOR3_HUMAN, also known as LAMTOR3, is a protein that functions as a scaffold within the human cell. It plays a crucial role in the regulation of the MAPK and MTOR signaling pathways by activating these important pathways responsible for many cellular processes. MEK-binding partner 1, also known as MEK partner 1 and Mitogen-activated protein kinase kinase 1-interacting protein 1, is another name for this protein. MP1, or Mitogen-activated protein kinase scaffold protein 1, is yet another designation for this important protein. The Ragulator complex protein LAMTOR3 also interacts with MP1. By rearranging this information in new and unique ways, we can gain a deeper understanding of LTOR3_HUMAN and its function within our bodies.
Source	Rabbit
Specificity	Total LAMTOR3 can be detected by the LAMTOR3 Antibody, which specifically targets endogenous levels of the protein. Let me rearrange the information for you in a slightly different manner: The LAMTOR3 Antibody is highly effective in identifying and quantifying endogenous levels of total LAMTOR3 present in biological samples.
Species Reactivity	Human;Mouse;Rat
Antigen	LAMTOR3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human LAMTOR3.
MW	14 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we were able to purify the antiserum through peptide affinity chromatography. The process involved separating the desired antibodies from other unwanted components, resulting in a highly purified product.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure maximum shelf life, it is recommended to store the product at a temperature of -20°C for a period of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles, as this can significantly impact its stability and efficacy. By following these guidelines, you can help ensure that the product maintains its quality and performance over an extended period of time.
Storage buffer	The recommended storage for Rabbit IgG is at -20 °C in phosphate buffered saline with a pH of 7.4. The solution should contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is advised to store the product as received and it will remain stable for 12 months from the date of receipt.
Target
Background	As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Celluar localization	Endosome;Extracellular region or secreted;Lysosome;Plasma Membrane;
UniPort	Q9UHA4