Rabbit Anti-Inhibin BetaB Polyclonal Antibody#abs131255
Please note that the price mentioned is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. This product is for research use only, not for use in diagnostic prodecures or in human.
Description
| Catalog-specification | Delivery time | USD price |
abs131255-100ug | 1-2 Weeks | 301.0 |
abs131255-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.
| Overview | |
catalog | abs131255 |
Description | Activins and inhibins are important regulators of follitropin secretion in the pituitary gland. While activins enhance this secretion, inhibins work to suppress it. These molecules have a diverse range of functions related to hormone secretion in the hypothalamus and pituitary, as well as gonadal hormone secretion, germ cell development, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development, and bone growth. Depending on the specific subunit composition, these proteins may either activate or inhibit certain functions in the body. Interestingly, inhibins and activins seem to counteract each other's effects, with inhibins working to oppose the actions of activins. |
| Other names | Activin B is also known as Activin beta B chain or Inhibin beta 2. It is a subunit of the Inhibin protein complex. The human gene encoding Activin B is called INHBB. Activin B plays a crucial role in various biological processes, including cell proliferation, differentiation, and apoptosis. It is involved in the regulation of reproductive functions, as well as embryonic development and tissue repair. Activin B is produced by several different cell types, including ovarian granulosa cells, testicular Sertoli cells, and placental cells. It exerts its effects by binding to specific cell surface receptors and activating intracellular signaling pathways. Overall, Activin B is a multifunctional protein that plays an important role in various physiological and pathological processes. |
| Source | Rabbit |
| Specificity | The Inhibin βB Antibody is capable of detecting total levels of endogenous Inhibin βB in the body. By utilizing this antibody, it is possible to accurately measure the amount of Inhibin βB present in a sample. This feature is useful in a variety of applications, ranging from research to clinical use. Overall, this antibody is a powerful tool for studying Inhibin βB and its effects on the body. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Zebrafish;Chicken;Pig;Sheep;Horse;Bovine; |
| Antigen | Inhibin βB |
| Application | WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000 |
| Immunogen | A human Inhibin βB synthesized peptide has been developed and is now available. This newly synthesized peptide is highly similar to the original protein and contains all of the essential amino acids necessary for its biological activity. Derived from the human Inhibin βB protein, this peptide is an excellent tool for researchers and scientists alike in a variety of fields. Its high similarity to natural proteins makes it an ideal candidate for use in drug development and other therapeutic applications. |
| MW | 45 kDa |
| Properties | |
Concentration | 1mg/ml |
| purification | Peptide affinity chromatography on SulfoLink™ Coupling Resin was employed to purify the antiserum. Let me generate similar content by rearranging the information while ensuring it remains based on the original text. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
| Celluar localization | Extracellular region or secreted; |
| UniPort | P09529 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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