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Rabbit Anti-IMMP2L Polyclonal Antibody#abs139150

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Description

Catalog-specification	Delivery time	USD price
abs139150-100ug	1-2 Weeks	301.0
abs139150-50ug	1-2 Weeks	201.0

Overview
catalog	abs139150
Other names	The protein encoded by EC 3.4.21 is known as IMP2 or IMP2 inner mitochondrial membrane peptidase like. This protein is similar to the inner mitochondrial membrane protease found in S. cerevisiae, and is involved in the proteolytic processing of membrane proteins. IMP2 like protein plays a crucial role in the maintenance of mitochondrial function and homeostasis. This mitochondrial inner membrane protease subunit 2 is an important component that regulates the quality control of mitochondrial proteins. OTTHUMP00000207168 and OTTHUMP00000207189 are other designations for this protein, which may also be referred to as IMP2-LIKE. Together, these terms describe a protein with an essential function in the mitochondria, functioning as a peptidase that plays a critical role in the processing of mitochondrial membrane proteins.
Source	Rabbit
Specificity	The IMMP2L Antibody is capable of identifying total IMMP2L present within the body without the need for external intervention. This allows for the identification and analysis of endogenous levels of IMMP2L with high accuracy and reliability. It is important to note that this antibody is highly specific and only detects total IMMP2L, making it an ideal tool for researchers looking to investigate the function and role of this essential protein.
Species Reactivity	Human;Mouse
Predictive reaction species	Xenopus;Bovine;Horse
Antigen	IMMP2L
Application	IHC at a dilution of 1:200, followed by WB at dilutions ranging from 1:1000 to 1:3000, is commonly performed for protein analysis. For immunofluorescence or immunocytochemistry (IF/ICC), a dilution of 1:100 to 1:500 is recommended. For ELISA using peptide antigens, a dilution range of 1:20000 to 1:40000 is usually used. It is important to note that these dilution factors are based on the original text information and may vary depending on the specific experimental conditions.
Immunogen	A synthesized peptide derived from human IMMP2L.
MW	20 kDa
Properties
Concentration	1mg/ml
purification	The purification of the antiserum was carried out via peptide affinity chromatography, which involved the utilization of SulfoLink™ Coupling Resin. The resin acted as a coupling agent for the peptide ligands, which facilitated the separation and purification of the antiserum from other molecules present in the initial mixture. This method ensured that the final antiserum product had a high purity level and was suitable for its intended application.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to keep it stored at a temperature of -20 °C for a period of one year. It is advised not to subject the product to repeated freeze/thaw cycles in order to avoid any harm to its composition and efficacy.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
Tissue specificity	Expressed in all tissues tested except adult liver and lung.
Celluar localization	Mitochondrion;
UniPort	Q96T52