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Rabbit Anti-ARL2BP Polyclonal Antibody#abs140828

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Description

Catalog-specification	Delivery time	USD price
abs140828-100ug	1-2 Weeks	301.0
abs140828-50ug	1-2 Weeks	201.0

Overview
catalog	abs140828
Other names	The ADP ribosylation factor like 2 binding protein, also known as ARF-like 2-binding protein, ARL2BP protein or Binder of ARF2 protein 1, is an important protein that plays a crucial role in a range of cellular processes. This protein is also known as Binder of Arl Two or Binder of Arl2, and it is believed to bind to and help regulate the activity of ARF-like protein 2. Additionally, AR2BP_HUMAN, Arf like 2 binding protein BART1 or BART also contribute to these functions. The Retinitis pigmentosa 66 (autosomal recessive) is a condition that is associated with mutations in ARL2BP, highlighting the critical role of this protein in maintaining healthy vision. Overall, ARL2BP is an important protein that regulates a variety of important cellular processes, including the regulation of cell cycle progression and vesicle trafficking. Understanding the functions of this protein is crucial for developing new therapeutics for a range of diseases, including cancer and neurodegenerative disorders.
Source	Rabbit
Specificity	Total ARL2BP can be detected by using the ARL2BP Antibody, which is capable of detecting the naturally occurring levels of this protein. The antibody is highly effective in recognizing endogenous ARL2BP.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Rabbit;Pig;Dog;Sheep;Bovine;
Antigen	ARL2BP
Application	To get optimal results in Western Blotting, we recommend using a dilution range of 1:500-1:1000. For Immunofluorescence and Immunocytochemistry, a dilution range of 1:100-1:500 is recommended. When performing ELISA with peptide, we suggest using a dilution range of 1:20000-1:40000 to achieve accurate results. It is important to note that proper optimization of the dilution ranges can lead to improved accuracy and sensitivity in these applications.
Immunogen	A synthesized peptide.
MW	25 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for up to one year. Be sure to avoid subjecting the product to repeated freeze/thaw cycles, as this can adversely affect its stability and effectiveness. For optimal results, it is important to follow the storage instructions carefully and maintain the product in a controlled environment.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Tissue specificity	Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
Celluar localization	Cytoskeleton;Cytosol;Mitochondrion;Nucleus;
UniPort	Q9Y2Y0