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Phospho-FANCA (Ser1149) Rabbit Polyclonal Antibody#abs138258

Description

Catalog-specification	Delivery time	USD price
abs138258-100ug	1-2 Weeks	301.0
abs138258-50ug	1-2 Weeks	201.0

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Overview
catalog	abs138258
Other names	FANCA, also known as FA 1, FA, FA H, FA1, FAA, FACA, FAH, Fanca, FANCA_HUMAN, FANCH, or Fanconi anemia complementation group A, is a protein associated with Fanconi anemia complementation group A. It plays a crucial role in the development of Fanconi anemia type 1. Additionally, it is also referred to as MGC75158 or Protein FACA. These different names all correspond to the same protein, FANCA.
Source	Rabbit
Specificity	The Phospho-FANCA (Ser1149) Antibody is capable of detecting levels of endogenous FANCA, but only when it has been phosphorylated at Ser1149. This is important information for those working with this antibody, as it ensures that they are able to identify the specific state of FANCA that they are interested in. By utilizing this antibody, researchers can gain a better understanding of the roles that phosphorylation plays in FANCA function and regulation. It is important to note that this antibody should only be used with caution and with proper controls, as false positives could result in inaccurate data.
Species Reactivity	Human;Mouse;Rat
Antigen	FANCA
Application	。Western Blot（WB），1:10001:3000。（IHC），1:200。/（IF/ICC），1:1001:500。（ELISA），1:200001:40000（）。，。
Immunogen	A peptide synthesized from human Phospho-FANCA (Ser1149) has been developed. The peptide closely resembles the original protein and is derived from the same source. It has been carefully designed to ensure that it has high similarity and can be used effectively in various applications. With the help of a skilled scientific team and advanced technology, this peptide has been synthesized with great accuracy and precision. Its potential uses in research and medicine are vast and could revolutionize the way we approach certain diseases and medical conditions. The development of this peptide is a significant step forward in the field of science and shows promise for the future of biomedical research.
MW	162 kDa
Properties
Concentration	1mg/ml
purification	By subjecting purified rabbit serum to sequential chromatography on phospho- and non-phospho-peptide affinity columns, the antibody was obtained through affinity purification. This process selectively isolated the antibody from the serum based on its affinity for phospho- and non-phospho-peptide columns.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated cycles of freezing and thawing, as this may affect its efficacy. Proper storage conditions are key to ensuring the longevity and potency of the product. So, please take care of the recommended storage conditions to ensure the effectiveness of the product.
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline at a pH of 7.4, 150mM NaCl, with the addition of 0.02% sodium azide and 50% glycerol. To maintain stability, the product should be stored at -20 °C and is deemed stable for up to 12 months from the date of receipt.
Target
Background	DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Posttranslational modification	Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H.
Celluar localization	Nucleus;
UniPort	O15360