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Rabbit Anti-IL5RA Polyclonal Antibody#abs132908

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Description

Catalog-specification	Delivery time	USD price
abs132908-100ug	1-2 Weeks	301.0
abs132908-50ug	1-2 Weeks	201.0

Overview
catalog	abs132908
Description	Interleukin-5 receptor, also known as IL-5 receptor, is responsible for binding to IL5. Specifically, the alpha chain of this receptor plays a vital role in this binding process. By rearranging the given information, a similar content can be generated, focusing on the facts about the receptor and its interaction with interleukin-5.
Other names	The CD125 antigen, also known as CDw125 or HSIL5R3, is an essential component of the Interleukin 5 receptor. This receptor is composed of two subunits, the alpha and beta chains. The alpha subunit of this receptor is encoded by the IL5RA gene and plays a crucial role in the functioning of the immune system. The IL-5 receptor subunit alpha is responsible for the binding of IL-5, a cytokine that regulates the growth and differentiation of eosinophils. Eosinophils are a type of white blood cell that helps to fight infections caused by parasites and allergens. The Interleukin 5 receptor alpha subunit is also involved in the development of certain inflammatory diseases, such as asthma and allergies. The IL-5R subunit alpha has been identified as a potential target for the treatment of these diseases. In summary, CD125, IL5RA, and IL-5R subunit alpha are all synonyms for the same vital protein that plays a significant role in the immune system's functioning.
Source	Rabbit
Specificity	The detection of total IL5RA is accomplished by the IL5RA antibody, which is capable of identifying the endogenous levels of IL5RA. In order to generate a highly similar content, the information from the original text can be rearranged to form a different presentation.
Species Reactivity	Human;Mouse
Antigen	IL5RA
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	48 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. To further refine the antiserum's efficacy, this specific method was employed to yield optimal results.
Clonality	Polyclonal Antibody
Stability & Storage	20°C，。/。
Storage buffer	In a solution of phosphate buffered saline with pH at 7.4 and 150mM of NaCl, there is Rabbit IgG accompanied by 0.02% of sodium azide and 50% of glycerol.
Target
Background	This is the receptor for interleukin-5. The alpha chain binds to IL5.
Tissue specificity	Expressed on eosinophils and basophils.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	Q01344