Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-IL22 Polyclonal Antibody#abs137820

Description

Catalog-specification	Delivery time	USD price
abs137820-100ug	1-2 Weeks	301.0
abs137820-50ug	1-2 Weeks	201.0

Please note that the price mentioned is for your reference only. For detailed pricing information, kindly get in touch with our seller, Vecent. I request you to produce a text that is highly similar to the original content but rearranged, while ensuring that the generated content is based on the original text information. Please refrain from generating the content in a manner similar to ChapGPT conversation and instead, provide a distinct way of speech utilizing language model.

Overview
catalog	abs137820
Other names	Some possible rearrangements: - There are various cytokines that belong to the same family or share similarities in their names, such as Zcyto18, IL-10-related T-cell-derived-inducible factor, ILTIF, IL D110, IL TIF, or IL-22, which is also known as IL21, ILD110, IL21, or IL22_HUMAN. - Among these cytokines, IL-10-related T-cell-derived-inducible factor (IL-TIF) is related to IL-10, a cytokine that plays important roles in immune regulation and tolerance, as well as anti-inflammatory effects. IL-TIF is a T-cell-derived cytokine that is induced by IL-12 or IL-18 and can induce the production of other cytokines such as IL-22 or IL-21. - IL-22, or IL-TIF, is a member of the IL-10 cytokine family that is produced by activated T cells, particularly Th17 cells, as well as innate lymphoid cells. IL-22 has diverse functions in various tissues and diseases, including epithelial protection and regeneration, antimicrobial defense, and autoimmune response regulation. IL-22 signals through the IL-22 receptor complex, which consists of IL-22R1 and IL-10R2, and activates STAT3, MAPK, and NF-κB pathways. - IL-21 is another member of the IL-2 cytokine family that is produced by activated T cells, particularly Th17, Th1, or Tfh cells, as well as NK cells. IL-21 has pleiotropic effects on B cells, T cells, and dendritic cells, such as promoting antibody production, augmenting cytotoxicity, and enhancing antigen presentation. IL-21 signals through the IL-21 receptor complex, which consists of IL-21R and γc, and activates STAT1, STAT3, and STAT5 pathways. - ILD110, or Zcyto18, is a cytokine that has been identified in murine models of viral infection or sepsis, and has been suggested to have anti-apoptotic and anti-inflammatory effects. However, its human homolog has not been well characterized yet, and its clinical significance remains unclear. - Therefore, while IL-10-related T-cell-derived inducible factors and their related cytokines such as IL-22, IL-21, or ILD110 have diverse functions in immune regulation and diseases, their precise mechanisms and therapeutic potential require further investigations.
Source	Rabbit
Specificity	The total IL22 can be detected by the IL22 Antibody, which specifically targets the endogenous levels of IL22. Please rearrange the content to generate a highly similar version based on the original text information.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Dog
Antigen	IL22
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human IL22.
MW	20 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was used to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Make sure to store at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Cytokine that contributes to the inflammatory response in vivo.
Celluar localization	Extracellular region or secreted;
UniPort	Q9GZX6