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Rabbit Anti-IL-32 Polyclonal Antibody#abs138086

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis IL-32 using K562 whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs138086-100ug	1-2 Weeks	301.0
abs138086-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs138086
Other names	Interleukin 32, also known as IL-32 or NK4, is a protein that is encoded by the IL32 gene. It exists in various isoforms, including IL 32alpha, IL 32beta, IL 32gamma, IL 32delta, and Interleukin 32 small. Its function is associated with inflammation, immunity and apoptosis. IL-32 is produced by various cells, including T-cells, natural killer cells and monocytes. It has been implicated in a number of different diseases, including inflammatory bowel disease, rheumatoid arthritis, and cancer. Studies have shown that the levels of IL-32 can correlate with the severity of these diseases. IL-32 has also been studied for its potential therapeutic applications. It has been found to have anti-tumor effects in pancreatic and lung cancer, suggesting it may have a role in cancer treatment. Overall, the varied isoforms of IL-32 and its role in inflammation, immunity and apoptosis make it a topic of interest for researchers in a variety of fields.
Source	Rabbit
Specificity	The IL-32 Antibody is capable of detecting the total IL-32 levels present in the body, thereby providing an effective means of measuring its endogenous concentration.
Species Reactivity	Human;Mouse
Antigen	IL-32
Application	The recommended dilution for Western Blot (WB) is between 1:1000 and 1:3000. For Immunohistochemistry (IHC), the suggested dilution is 1:200. If you are using ELISA with a peptide, the ideal dilution range is between 1:20000 and 1:40000.
Immunogen	A synthesized peptide derived from human IL-32.
MW	26 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.
Tissue specificity	Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells.
Celluar localization	Cytosol;Extracellular region or secreted;
UniPort	P24001