Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-CCNY Polyclonal Antibody#abs132687

Please note that the stated price is merely a reference and for detailed pricing information, kindly contact our sales representative Vecent. Thank you. As a language model AI, I communicate differently from ChapGPT but rest assured that the content I generate is based entirely on the original...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs132687-100ug	1-2 Weeks	301.0
abs132687-50ug	1-2 Weeks	201.0

Overview
catalog	abs132687
Other names	C10orf9, also known as Cyclin box carrying protein 1 or CBCP1, is an intriguing gene located on chromosome 10. It encodes a protein called Cyclin box protein 1 or CCNX, which plays a crucial role in cell cycle regulation. CCNX, also referred to as Cyclin X or Cyclin Y, belongs to the Cyclin fold protein family. The function of CCNX is still under investigation, but it is believed to be involved in cell division and proliferation. Despite its importance, much remains unknown about the exact mechanisms by which C10orf9 and CCNX contribute to cellular processes. Further research is required to unveil the complete picture of their functions and potential implications in various biological contexts.
Source	Rabbit
Specificity	The detection of endogenous levels of total CCNY can be achieved using the CCNY antibody. To ensure accurate results, it is important to use an antibody that specifically targets CCNY. This allows researchers to gain insights into the expression levels and localization of CCNY in various biological samples. By detecting endogenous CCNY, scientists can investigate its role in cellular processes and potentially develop novel therapeutic approaches targeting this protein.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Chicken;Sheep;Dog;Horse;Bovine;
Antigen	CCNY
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	39 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. The process involved carefully isolating the desired peptides and removing any impurities to obtain a highly purified sample. This technique is widely used in the purification of biological molecules and is suitable for high-throughput applications. Overall, our successful purification of the antiserum will enable further downstream applications and contribute to advancing scientific research.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the product is stored at -20 °C for a duration of one year, while taking precautions to avoid repeated freeze/thaw cycles. It is crucial to prevent alterations in temperature as this may affect the quality and efficacy of the product.
Storage buffer	The buffer solution for Rabbit IgG contains sodium azide, 150mM NaCl, and glycerol in a pH 7.4 phosphate solution. It also contains 50% glycerol to ensure stability and longevity of the product. This solution is ready for use and does not require any additional preparation before use. It is recommended to store the solution at a temperature range between 2°C to 8°C to ensure extended shelf life.
Target
Background	Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Tissue specificity	Widely expressed.
Posttranslational modification	Ubiquitinated; leading to its degradation.Heavily phosphorylated. Phosphorylation at Ser-71 and Ser-73 by CDK14 is enhanced during the G2 and M cell cycle phases, and creates a phosphodegron triggering SCF-dependent ubiquitination.
Celluar localization	Extracellular region or secreted;Nucleus;Plasma Membrane;
UniPort	Q8ND76