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Rabbit Anti-IGFBPL1 Polyclonal Antibody#abs132891

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Description

Catalog-specification	Delivery time	USD price
abs132891-100ug	1-2 Weeks	301.0
abs132891-50ug	1-2 Weeks	201.0

Overview
catalog	abs132891
Other names	IGFBP-related protein 10, also known as IGFBP-RP4 or IGFBPL1, is an important molecule involved in regulating insulin-like growth factor (IGF) binding. It is commonly referred to as IGFBPRP4 or insulin-like growth factor-binding protein-related protein 4. Additionally, it is also known as insulin-like growth factor-binding protein-like 1. This protein plays a significant role in modulating the activity of IGF and is considered an essential player in various physiological processes. Understanding the functions and mechanisms of IGFBP-related protein 10 offers valuable insights into the intricate regulation of growth factors and their impact on cellular processes.
Source	Rabbit
Specificity	The total IGFBPL1 levels in the body can be detected using the IGFBPL1 antibody which is effective in identifying the endogenous levels of the protein.
Species Reactivity	Human;Mouse
Predictive reaction species	Rabbit
Antigen	IGFBPL1
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	29 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography involving SulfoLink™ Coupling Resin was employed to purify the antiserum. The purification process successfully yielded a highly pure antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to store the product at a temperature of -20 °C for a duration of one year. To maintain its quality, it is important to avoid subjecting the product to repeated freeze-thaw cycles.
Storage buffer	The rabbit IgG is suspended in a solution containing phosphate buffered saline with a pH of 7.4, along with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This well-balanced solution provides a stable environment for the IgG and helps to maintain its integrity. Additionally, the inclusion of sodium azide helps to prevent bacterial growth, ensuring the purity of the solution. Overall, this formulation provides an ideal environment for the storage and use of rabbit IgG in various applications.
Target
Background	IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein.
Tissue specificity	Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung.
Celluar localization	Extracellular region or secreted;
UniPort	Q8WX77