Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-IGFBP5 Polyclonal Antibody#abs136094

Please note that the price mentioned is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Kindly refrain from using the content generated by ChapGPT to engage in conversation, and instead speak in a manner that produces text that is...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs136094-100ug	1-2 Weeks	301.0
abs136094-50ug	1-2 Weeks	201.0

Overview
catalog	abs136094
Description	IGFBP5, also known as IBP5, plays a crucial role in extending the lifespan of IGFs and has the ability to either inhibit or enhance the growth-promoting effects of IGFs in cell culture. It modulates the interaction between IGFs and their receptors present on the cell surface. Specifically, this antibody has high specificity towards IGFBL5 and can effectively target and interact with it. To summarize, IGFBP5 is a key player in regulating the activity of IGFs and their receptors, thereby influencing cellular growth processes.
Other names	IGF binding protein 5, also known as IBP-5 or IGFBP-5, is a protein that binds to and regulates the activity of insulin-like growth factors. It is encoded by the IBP5_HUMAN gene and plays a crucial role in cellular growth and development. IGFBP-5 is involved in modulating the actions of insulin-like growth factors, which are essential for normal growth and metabolism. Insulin-like growth factor binding protein 5, or IGFBP-5, is a vital component in controlling the actions of insulin-like growth factors (IGFs). It is encoded by the IBP5_HUMAN gene and is responsible for regulating cellular growth and development. IGFBP-5 binds to IGFs and modulates their activity, thus playing a crucial role in normal growth and metabolism. IGFBP-5, also referred to as IGF-binding protein 5, is an important protein linked to the insulin-like growth factor system. It is encoded by the IGFBP5 gene and has significant implications in cellular growth and development. IGFBP-5 binds to IGFs, thereby regulating their activity and influencing various biological processes related to growth and metabolism. IBP-5, or IGF binding protein 5, is a protein that interacts with insulin-like growth factors. Encoded by the IBP5_HUMAN gene, this protein plays a pivotal role in cellular growth and development. By binding to IGFs, IBP-5 modulates their actions, thus exerting control over essential processes like growth and metabolism. Insulin-like growth factor-binding protein 5, commonly known as IGFBP-5 or IGF BP5, is a crucial protein involved in regulating insulin-like growth factors. Encoded by the IGFBP5 gene, it plays a significant role in cellular growth and development. IGFBP-5 interacts with IGFs, contributing to the modulation of their activity and impacting essential functions such as growth and metabolism. IGFBP5, also called IGFBP-5 or insulin-like growth factor-binding protein 5, is a protein responsible for binding and regulating the activity of insulin-like growth factors. Encoded by the IBP5_HUMAN gene, IGFBP5 plays a pivotal role in cellular growth and development. By interacting with IGFs, this protein influences crucial processes like growth and metabolism, making it integral to overall health.
Source	Rabbit
Specificity	The overall levels of total IGFBP5 within an organism can be detected using the IGFBP5 Antibody. This antibody specifically targets the endogenous levels of IGFBP5, allowing for accurate measurement and analysis. By detecting and quantifying IGFBP5, researchers and scientists can gain insights into its role and function in various biological processes.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Chicken;Rabbit;Pig;Dog;Bovine;Sheep;Horse;
Antigen	IGFBP5
Application	For Western blot, the recommended dilution range is 1:500-1:2000. For Immunohistochemistry, the optimal dilution range is 1:50-1:200. In ELISA testing using a peptide, the dilution range is suggested to be between 1:20000 to 1:40000. Make sure to follow these recommended dilution ranges for best results in your experiments.
Immunogen	A synthesized peptide derived from human IGFBP5.
MW	31kDa
Properties
Concentration	1mg/ml
purification	In the purification process, SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to effectively purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Tissue specificity	Osteosarcoma, and at lower levels in liver, kidney and brain.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	P24593