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Rabbit Anti-GPR64 Polyclonal Antibody#abs133137

Please note that the mentioned price is only for your reference, and for detailed price information, kindly get in touch with our seller, Vecent. Feel free to contact him for further assistance. Western blot analysis of GPR64 expression in A431 whole cell lysate ,The lane on the left is treated...

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Description

Catalog-specification	Delivery time	USD price
abs133137-100ug	1-2 Weeks	301.0
abs133137-50ug	1-2 Weeks	201.0

Please note that the mentioned price is only for your reference, and for detailed price information, kindly get in touch with our seller, Vecent. Feel free to contact him for further assistance.

Overview
catalog	abs133137
Other names	TM7LN2; FLJ00282; MGC104454; MGC138738; MGC138739; G protein coupled receptor 64; G protein coupled receptor epididymis specific; GPR64; GPR 64; HE 6; He 6 receptor; HE6; He6 receptor; Epididymis specific protein 6. Let's rearrange the content: The protein TM7LN2, also known as FLJ00282, is encoded by the genes MGC104454, MGC138738, and MGC138739. It is a G protein coupled receptor 64, specifically expressed in the epididymis. This receptor, known as GPR64 or HE6, plays a crucial role in various biological processes. Its function and significance make it an important target for research and potential therapeutic interventions. By studying the HE6 receptor, scientists aim to unravel its precise mechanisms and explore its implications in reproductive health and other related fields.
Source	Rabbit
Specificity	The detection of total GPR64 at its endogenous levels is achievable using the GPR64 antibody. You can rely on this antibody to accurately identify and measure the presence of GPR64 in biological samples. By detecting and quantifying the total GPR64 protein, researchers can gain insights into its expression and function in various cellular processes. This antibody is a valuable tool in studying the role of GPR64 in different physiological and pathological conditions.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Dog;
Antigen	GPR64
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	112 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography. To ensure high purity levels, rigorous procedures were followed during the process. The resulting antiserum was of exceptional quality and suitable for various research applications.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage, it is recommended to keep the store at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the store to repeated freeze/thaw cycles as it may negatively affect the quality of the products.
Storage buffer	The solution contains Rabbit IgG dissolved in a buffer of phosphate and saline with a pH of 7.4. The solution also has 150mM of NaCl and 0.02% of sodium azide as preservatives. Additionally, 50% glycerol has been added to the solution to enhance its stability.
Target
Background	Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility. May regulate fluid exchange within epididymis.
Tissue specificity	Epididymis-specific expression (at protein level). Both subunits are associated with apical membranes of efferent ductule and proximal epididymal duct epithelia. Mainly expressed in the nonciliated principal cells of the proximal excurrent ducts. Specifically over-expressed in Ewing sarcomas but also up-regulated in a number of carcinomas derived from prostate, kidney or lung.
Posttranslational modification	Proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.Highly glycosylated.
Celluar localization	Cytosol;Extracellular region or secreted;Plasma Membrane;
UniPort	Q8IZP9