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Rabbit Anti-GORASP1 Polyclonal Antibody#abs139056

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Description

Catalog-specification	Delivery time	USD price
abs139056-100ug	1-2 Weeks	301.0
abs139056-50ug	1-2 Weeks	201.0

Overview
catalog	abs139056
Other names	FLJ23443 is a protein found in the peripheral membrane of the Golgi apparatus. It is also known as p65 and is involved in various cellular processes. Another Golgi protein is Golgi phosphoprotein 5, which plays a role in phosphorylation events within the Golgi apparatus. Additionally, Golgi reassembly and stacking protein 1, also known as GRASP65, is responsible for the reassembly and stacking of Golgi cisternae during cell division. It is a 65-kDa protein that is essential for maintaining the structural integrity of the Golgi apparatus. Another name for GRASP65 is Golgi reassembly-stacking protein 1. GOLPH5, also known as Gorasp1, is yet another Golgi protein. It performs multiple functions, including regulating protein transport and membrane trafficking between the Golgi apparatus and the endoplasmic reticulum. It is a crucial component in maintaining Golgi structure and function. Overall, these proteins mentioned above, FLJ23443, Golgi phosphoprotein 5, Golgi reassembly and stacking protein 1 (GRASP65), and GOLPH5 (Gorasp1), are all involved in various aspects of Golgi apparatus functionality and contribute to the proper functioning of intracellular transport and protein trafficking processes.
Source	Rabbit
Specificity	The total GORASP1 levels can be detected by the GORASP1 Antibody, which specifically recognizes the endogenous levels of this protein. Let's rearrange the content to present it in a highly similar way: - The GORASP1 Antibody is capable of detecting the total levels of endogenous GORASP1 protein. - The endogenous levels of total GORASP1 can be detected using the GORASP1 Antibody. - By utilizing the GORASP1 Antibody, it is possible to measure the total endogenous levels of GORASP1 protein. - Using the GORASP1 Antibody, researchers can reliably detect the total amount of endogenous GORASP1 protein.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine
Antigen	GORASP1
Application	The recommended dilution for Western Blot (WB) is 1:1000-3000, while for Immunohistochemistry (IHC) it is 1:200. For ELISA using a peptide, the suggested dilution range is 1:20000-1:40000. It is important to follow these dilution guidelines to ensure accurate and reliable results in your experiments.
Immunogen	A synthesized peptide derived from human GORASP1.
MW	46 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. A highly similar statement can be generated by rearranging the words in the original text and maintaining its core message.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality and effectiveness of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles as this can lead to degradation and loss of potency. Therefore, proper storage and handling should be observed to ensure optimal performance of the product over time.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis (By similarity). Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes (PubMed:16489344).
Posttranslational modification	Phosphorylated by CDC2/B1 and PLK kinases during mitosis. Phosphorylation cycle correlates with the cisternal stacking cycle. Phosphorylation of the homodimer prevents the association of dimers into higher-order oligomers, leading to cisternal unstacking.Target for caspase-3 cleavage during apoptosis. The cleavage contributes to Golgi fragmentation and occurs very early in the execution phase of apoptosis (By similarity).
Celluar localization	Golgi apparatus;
UniPort	Q9BQQ3