Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-Glut4 (R271) PAb Polyclonal Antibody#abs131486

Description

Catalog-specification	Delivery time	USD price
abs131486-100ug	In Stock	301.0
abs131486-50ug	In Stock	201.0

Please note that the price mentioned above is only for your reference, and for further details on the pricing, please get in touch with our seller, Vecent. It is important to keep in mind that the above information serves as a rough estimate and may not be completely accurate. Therefore, we highly recommend contacting Vecent, who will be able to provide you with all the necessary information on pricing and other related queries. Thank you for your understanding.

Overview
catalog	abs131486
Description	When insulin is introduced, the transportation system in our body undergoes a significant change. A protein called Glut4, which is responsible for transporting glucose, is rapidly transported from a storage site to the cell surface. This process involves binding glucose molecules to the Glut4 protein. On the other hand, the Glut1 transporter, which is present in most cells in our body, is constantly present on the cell surface. It responds to insulin differently and does not experience dramatic changes following its introduction.
Other names	The insulin-responsive glucose transporter type 4, also known as GLUT 4, is a protein that facilitates the transport of glucose across the cell membrane. This protein is specifically responsive to insulin, which means that its expression and activity are regulated by insulin levels in the body. GLUT 4 is a member of the solute carrier family 2, which includes other facilitated glucose transporters. However, unlike other members of this family, GLUT 4 is specifically insulin-responsive. This means that its expression and activity are tightly controlled by insulin, which helps to regulate glucose uptake by cells in response to changes in blood glucose levels. Overall, the unique properties of GLUT 4 make it a key player in glucose homeostasis. By regulating the activity of this protein, the body is able to maintain healthy levels of glucose in the blood, which is critical for overall health and well-being.
Source	Rabbit
Specificity	The Glut 4 pAb antibody is capable of detecting the complete expression of Glut 4 pAb at physiological levels. A highly analogous content can be created by rearranging the original text information to convey the same meaning.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit
Antigen	Glut4 pAb
Application	The recommended dilution ranges for our antibodies are as follows: 1:500-1:2000 for western blotting, 1:50-1:200 for immunohistochemistry, and 1:20000-1:40000 for ELISA using peptide. These dilution ranges are designed to help maximize the sensitivity and specificity of our antibodies and are based on our extensive testing and validation processes. Whether you are using our antibodies for research, diagnostics, or therapeutics, we are committed to providing you with the highest quality reagents for your applications. So, choose our antibodies with confidence and rest assured that you are getting the best possible results.
Immunogen	A synthetic peptide has been created using human Glut 4 pAb as a template. The resulting molecule is highly similar in composition to the original protein, and is expected to have similar functions and properties. The peptide may be useful in a variety of applications, including research into the structure and function of Glut 4, and in the development of new therapies for conditions associated with impaired glucose metabolism.
MW	54 kDa
Properties
Concentration	1mg/ml
purification	The purification process of the antiserum involved the utilization of SulfoLink™ Coupling Resin through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Insulin-regulated facilitative glucose transporter.
Tissue specificity	Skeletal and cardiac muscles; brown and white fat.
Posttranslational modification	Sumoylated.
Celluar localization	Cytosol;Endosome;Extracellular region or secreted;Golgi apparatus;Plasma Membrane;
UniPort	P14672