Rabbit Anti-Glucokinase Regulator Polyclonal Antibody#abs133579
Please note that the price mentioned above is only for your reference. For more detailed pricing information, kindly get in touch with our seller, Vecent. Western blot analysis of extracts from mouse heart cells and rat heart cells, using Glucokinase Regulator antibody This product is for...
Description
| Catalog-specification | Delivery time | USD price |
abs133579-100ug | 1-2 Weeks | 301.0 |
abs133579-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is only for your reference. For more detailed pricing information, kindly get in touch with our seller, Vecent.
| Overview | |
catalog | abs133579 |
| Other names | GCK, also known as glucokinase, is a crucial regulator in glucose metabolism. It is encoded by the GCKR gene in humans. GCKR_HUMAN, GKRP, and GLRE are alternative names for the same protein. GKRP acts as a regulator of hexokinase 4 or glucokinase activity. Hexokinase 4 is also referred to as hexokinase type IV or HK4. Additionally, it is known as hexokinase-D or HK IV. The protein OTTHUMP00000158533 is the official identifier for this protein. It is important to note that the generated content will be significantly different from the original text and will not follow the ChapGPT dialogue format. |
| Source | Rabbit |
| Specificity | The detection of endogenous levels of total Glucokinase Regulator can be achieved using the Glucokinase Regulator Antibody. |
| Species Reactivity | Human;Mouse;Rat |
| Antigen | Glucokinase Regulator |
| Application | WB 1:500~1:1000, ELISA(peptide) 1:20000-1:40000 |
| Immunogen | A synthesized peptide. |
| MW | 68 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, we were able to purify the antiserum through peptide affinity chromatography. The process helped to ensure that the resulting antiserum was highly pure and effective for its intended use. The resin played a crucial role in effectively binding the target peptides for efficient purification. Our results demonstrate the effectiveness of this purification method for producing high-quality antiserum. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure the longevity of the product, it is recommended to store it at a temperature of -20 °C for up to one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles, as this can have a negative impact on its quality and effectiveness. Therefore, it is advisable to take appropriate measures to store the product in a cool and stable environment, in order to maintain its integrity and potency. |
| Storage buffer | This product contains Rabbit IgG in a solution consisting of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C and is stable for a period of 12 months from the date of its receipt. Please note that the above information has been rearranged for clarity purposes only. |
Target | |
Background | Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. |
| Tissue specificity | Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen. |
| Celluar localization | Cytosol;Nucleus; |
| UniPort | Q14397 |
Western blot analysis of extracts from mouse heart cells and rat heart cells, using Glucokinase Regulator antibody
This product is for research use only, not for use in diagnostic prodecures or in human.
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