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Rabbit Anti-FXR2 Polyclonal Antibody#abs133497

Please note that the price provided above is for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis of extracts from COLO205 cells, using FXR2 antibody. This product is for research use only, not for use in...

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Description

Catalog-specification	Delivery time	USD price
abs133497-100ug	1-2 Weeks	301.0
abs133497-50ug	1-2 Weeks	201.0

Please note that the price provided above is for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs133497
Other names	FMR1L2, also known as Fragile X mental retardation 1 like 2 or Fragile X mental retardation autosomal homolog 2, is a gene that is implicated in Fragile X mental retardation syndrome. This syndrome is characterized by intellectual disability and various physical and behavioral symptoms. Among the multiple functions of FMR1L2, it is involved in the regulation of synaptic plasticity, the process by which the connections between neurons in the brain are strengthened or weakened. Fragile X mental retardation gene autosomal homolog 2, abbreviated as FXR2, is another name for FMR1L2. This gene is highly similar to another gene called Fragile X mental retardation gene 1 (FMR1). Both FXR2 and FMR1 are part of a family of genes that are implicated in Fragile X syndrome, a genetic disorder that causes intellectual disability and developmental delays. FXR2 encodes for a protein called fragile X mental retardation syndrome-related protein 2 (FXR2P). This protein is thought to play a role in the regulation of mRNA transport and translation, particularly in the synapses of neurons. It is believed that FXR2P helps to control the production of proteins that are important for normal brain development and function. Overall, the research on FMR1L2 and its associated protein FXR2P is still ongoing, and scientists continue to study their functions and potential implications in Fragile X syndrome and other cognitive disorders. Knowing more about these genes and their protein products may provide valuable insights into the underlying mechanisms of these conditions and potentially lead to the development of targeted therapies in the future.
Source	Rabbit
Specificity	The total FXR2 endogenous levels can be detected using the FXR2 Antibody. We can rearrange the given content to generate a similar but different version.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	FXR2
Application	For Western blotting, the recommended dilution is between 1:500 to 1:1000. When performing immunohistochemistry, it's recommended to use a dilution range of 1:50 to 1:200. For immunofluorescence or immunocytochemistry, a dilution of 1:100 to 1:500 is appropriate. If you plan on using ELISA with a peptide, the suggested dilution range is between 1:20000 to 1:40000. It's important to follow these guidelines to ensure accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	74 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. The end result was a highly refined and purified antiserum product.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to keep the product at a temperature of -20 °C for a period of one year. To prevent any damage, avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	RNA-binding protein.
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;
UniPort	P51116