Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-FIGF Polyclonal Antibody#abs135847

Please note that the price provided above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent. Instead of generating content using the conversation style of ChapGPT, I will deliver the information in a completely different manner using a...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs135847-100ug	1-2 Weeks	301.0
abs135847-50ug	1-2 Weeks	201.0

Overview
catalog	abs135847
Description	This particular gene encodes a protein that belongs to the PDGF/VEGF family, specifically involved in the processes of angiogenesis, lymphangiogenesis, and growth of endothelial cells. The protein is secreted and undergoes a complex proteolytic maturation, resulting in multiple forms that can bind and activate VEGFR-2 and VEGFR-3 receptors. Interestingly, this protein shares both structural and functional similarities with vascular endothelial growth factor C. Moreover, there has been evidence of read-through transcription occurring between this gene and the adjacent PIR locus. These details were sourced from RefSeq in February 2011.
Other names	One of the growth factors that is induced by the c-fos gene is known as c-fos-induced growth factor, or FIGF for short. Another name for this growth factor is vascular endothelial growth factor D, or VEGF D. This factor plays an important role in promoting the growth and development of blood vessels. The precursor form of VEGF D is also sometimes referred to as VEGF-D or VEGFD. In humans, this factor can help to control angiogenesis, or the formation of new blood vessels, which is important for wound healing and other processes in the body. Overall, c-fos-induced growth factor is a vital molecule that helps to regulate blood vessel development and maintain the health of our cardiovascular system.
Source	Rabbit
Specificity	The total FIGF levels in the body can be detected by the FIGF Antibody, which specifically recognizes the endogenous FIGF protein.
Species Reactivity	Human;Mouse;Rat
Antigen	FIGF
Application	，： WB1:500-1:2000，IHC1:50-1:200，ELISA（）1:20000-1:40000。
Immunogen	A synthesized peptide derived from human FIGF.
MW	40kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum. Let's rearrange the content: The purification of the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
Tissue specificity	Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
Posttranslational modification	Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
Celluar localization	Extracellular region or secreted;
UniPort	O43915