Rabbit Anti-FBXO32 Polyclonal Antibody#abs136595

Rabbit Anti-FBXO32 Polyclonal Antibody#abs136595

Please note that the mentioned price is for your reference only. For detailed pricing information, we kindly request you to reach out to our seller, Vecent. Feel free to contact Vecent for accurate pricing details. This product is for research use only, not for use in diagnostic prodecures or in...

Description

Catalog-specificationDelivery timeUSD price

abs136595-50ug

1-2 Weeks

201.0

abs136595-100ug

1-2 Weeks

301.0

Please note that the mentioned price is for your reference only. For detailed pricing information, we kindly request you to reach out to our seller, Vecent. Feel free to contact Vecent for accurate pricing details.


Overview

catalog

abs136595
Other namesThe gene 4833442G10Rik also goes by several other names, including AI430017, Atrogin 1, Atrogin-1, ATROGIN1, and Atrophy gene 1. It is also referred to by various protein names, such as F box only protein 32, F-box only protein 32, F-box protein 32, FBX32_HUMAN, fbxo25, FBXO32, FLJ32424, MAFbx, MGC108443, MGC137646, MGC33610, Muscle atrophy F box, and Muscle atrophy F box protein. This gene is known to play a role in muscle atrophy and is associated with the ubiquitin-proteasome pathway. It is a member of the F-box protein family and functions as a substrate recognition component of an SCF (SKP1-CUL1-F-box protein) ubiquitin-protein ligase complex. This complex helps to target specific proteins for degradation, which is important for maintaining proper cellular function. Through its various names and roles, 4833442G10Rik is a critically important gene for cellular health and muscle function.
SourceRabbit
SpecificityThe total levels of endogenous FBXO32 can be detected using the FBXO32 antibody.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesPig;Rabbit;Sheep;Dog;Bovine;Horse;
AntigenFBXO32
ApplicationFor Western blotting assays, a suitable dilution range is 1:500 to 1:1000, while for immunohistochemistry staining, a dilution of 1:50 to 1:100 is recommended. For ELISA tests using peptides, the optimal dilution factors are between 1:20000 and 1:40000. These dilution ranges are critical for achieving accurate and reliable results in these assays.
ImmunogenA synthesized peptide derived from human FBXO32.
MW25kDa
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was utilized in the purification process of the antiserum through peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageTo preserve the material, it is recommended to keep it stored at a temperature of -20 °C for up to a year. To prevent damage to the substance, it is important to avoid subjecting it to repeated cycles of freezing and thawing. Take caution to ensure that the material is stored properly to maintain its efficacy.
Storage bufferThis product consists of Rabbit IgG in a phosphate buffered saline solution with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol, allowing for optimal storage at -20 °C. With a stable shelf life of 12 months from the date of receipt, this product is a reliable source for your research needs.

Target

Background

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.

Tissue specificitySpecifically expressed in cardiac and skeletal muscle.
Celluar localizationCytosol;Nucleus;
UniPortQ969P5


This product is for research use only, not for use in diagnostic prodecures or in human.


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