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Rabbit Anti-FBLN5 Polyclonal Antibody#abs141135

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Description

Catalog-specification	Delivery time	USD price
abs141135-50ug	1-2 Weeks	201.0
abs141135-100ug	1-2 Weeks	301.0

Overview
catalog	abs141135
Other names	ARCL1A; ARMD3; Dance; Developmental arteries and neural crest EGF-like protein; Developmental arteries and neural crest EGF like protein; EVEC; Fbln5; FIBL 5; FIBL-5; Fibulin-5; FLJ90059; UP50; Urine p50 protein; ADCL2; FBLN5_HUMAN; ARCL1A; ARMD3; Dance; Developmental arteries and neural crest EGF-like protein; Developmental arteries and neural crest EGF like protein; EVEC; Fbln5; FIBL 5; FIBL-5; Fibulin-5; FLJ90059; UP50; Urine p50 protein; ADCL2; FBLN5_HUMAN These terms represent various proteins and conditions related to developmental arteries, neural crest, and dance. ARCL1A and ARMD3 are disorders associated with abnormalities in the arteries and neural crest development. Dance refers to the artistic form of expression through body movements in rhythm. Developmental arteries and neural crest EGF-like protein is a type of protein involved in the development of arteries and neural crest cells. EVEC is another protein associated with developmental processes. Fbln5, also known as FIBL 5 or Fibulin-5, is a human protein encoded by the FBLN5_HUMAN gene. It plays a role in the extracellular matrix. FLJ90059 and UP50 are alternative names for Fibulin-5. Urine p50 protein is a protein found in urine samples. These terms encompass a range of topics related to biology, genetics, and dance.
Source	Rabbit
Specificity	The FBLN5 Antibody is capable of detecting the total levels of endogenous FBLN5. If you want to create similar content, you can rearrange the original text information while maintaining its overall meaning.
Species Reactivity	Human;Mouse;Rat
Antigen	FBLN5
Application	The recommended dilutions for Western blot are 1:500 to 1:1000, for immunofluorescence/immunocytochemistry are 1:100 to 1:500, and for ELISA using a peptide substrate are 1:20000 to 1:40000. It is important to dilute the samples accordingly to ensure accurate results in these assays.
Immunogen	A synthesized peptide.
MW	50 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography. It was a process that ensured a highly efficient and effective removal of any impurities that may have been present in the antiserum. Overall, this approach allowed for the production of a purified antiserum that was of very high quality and free from any unwanted contaminants.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	This product is Rabbit IgG packaged in phosphate buffered saline with a pH value of 7.4. It also contains 150 millimoles of sodium chloride, 0.02% sodium azide, and 50% glycerol to ensure its stability. Storage at a temperature of -20 °C is recommended, as it can remain stable for up to 12 months from the date of receipt.
Target
Background	Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).
Tissue specificity	Expressed in skin fibroblasts (at protein level)(PubMed:17035250). Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823).
Posttranslational modification	N-glycosylated.
Celluar localization	Extracellular region or secreted;
UniPort	Q9UBX5

This product is for research use only, not for use in diagnostic prodecures or in human.

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