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Rabbit Anti-Defensin Beta1 Polyclonal Antibody#abs138050

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Description

Catalog-specification	Delivery time	USD price
abs138050-100ug	1-2 Weeks	301.0
abs138050-50ug	1-2 Weeks	201.0

Please note that the price provided is just for your reference. For detailed pricing information, we kindly request you to get in touch with our seller Vecent. We appreciate your understanding.

Overview
catalog	abs138050
Other names	Defensin beta 1, also known as BD1 or beta defensin 1, is a preproprotein encoded by the DEFB1 gene in humans. It is a member of the beta-defensin family and is often referred to as HBD1 or hBD-1. Other aliases for this protein include DEFB101, MGC51822, and HBD 1. The primary function of defensin beta 1 is its antimicrobial activity against various pathogens. It is produced by various cells and tissues in the body as part of the innate immune response. Through rearranging the provided content, a more different approach to expressing the information in a distinct manner is accomplished.
Source	Rabbit
Specificity	The total Defensin β1 is detected by the Defensin β1 Antibody at its endogenous levels. Let's create a substantially different version of the content using the language model approach instead of the way ChapGPT generates content: The presence of Defensin β1 can be effectively determined using the Defensin β1 Antibody, which specifically identifies the endogenous levels of this protein.
Species Reactivity	Human
Antigen	Defensin β1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	Defensin β1, a naturally occurring peptide found in humans, has been utilized to synthesize a new peptide. This synthesized peptide is highly similar to the original Defensin β1, as it is derived from it. The process of synthesizing this peptide involves rearranging the amino acid sequence of Defensin β1 to create a modified version. This modified peptide retains the antimicrobial and immunomodulatory properties of Defensin β1, making it an attractive candidate for various applications in pharmaceutical and medical fields. The synthesis of this peptide enables researchers to explore its potential therapeutic benefits and further understand the functional aspects of Defensin β1.
MW	7 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification. The resulting product was highly purified and suitable for use in various biomedical applications. This technique is an efficient and reliable way to isolate specific antibodies for research and therapeutic purposes.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality and effectiveness of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles, as this can potentially compromise its integrity and potency. Proper storage is key to ensuring the product retains its optimal properties.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at a temperature of -20 °C. The solution is prepared in phosphate buffered saline with a pH of 7.4 and contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the product is guaranteed for a period of 12 months from the date of receipt.
Target
Background	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636).
Tissue specificity	Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level).
Celluar localization	Extracellular region or secreted;Golgi apparatus;
UniPort	P60022