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Rabbit Anti-CPM Polyclonal Antibody#abs140978

Rabbit Anti-CPM Polyclonal Antibody#abs140978

Please note that the price mentioned above is for reference only, and for detailed pricing information, please get in touch with our sales representative Vecent. It is important to reiterate that the aforementioned price should not be taken as the final price, and for accurate pricing details,...

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Description

Catalog-specificationDelivery timeUSD price

abs140978-100ug

1-2 Weeks

301.0

abs140978-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is for reference only, and for detailed pricing information, please get in touch with our sales representative Vecent. It is important to reiterate that the aforementioned price should not be taken as the final price, and for accurate pricing details, Vecent would be the best point of contact.


Overview

catalog

abs140978
Other namesCarboxypeptidase M, also known as CPM or renal carboxypeptidase, is an enzyme that belongs to the family of carboxypeptidases. Another name for the enzyme is urinary carboxypeptidase B. CPM is responsible for the cleavage of carboxy-terminal amino acids from proteins and peptides. The enzyme plays a crucial role in various physiological processes, including blood coagulation, metabolism, and the immune response. The human CBPM_HUMAN sequence can be used to study the protein's structure and function, offering insights into potential therapeutic targets for various diseases. Overall, Carboxypeptidase M is a vital enzyme with many potential therapeutic applications that can benefit human health in many ways.
SourceRabbit
SpecificityThe CPM Antibody is specifically designed to detect the natural levels of total CPM protein in cells. By targeting this endogenous protein, it allows researchers to accurately measure and analyze CPM expression in various biological samples. This highly reliable antibody is an invaluable tool for studying the functions and regulations of CPM, providing insights into its roles in physiology and pathology.
Species ReactivityHuman
AntigenCPM
ApplicationThe recommended dilution for Western blotting is 1:500 to 1:1000, while for immunofluorescence or immunocytochemistry it is 1:100 to 1:500. For ELISA with peptide detection, the suggested dilution range is 1:20000 to 1:40000.
ImmunogenA synthesized peptide.
MW51 KD
Properties

Concentration

1mg/ml

purificationUsing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageEnsure that the product is stored at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to multiple cycles of freezing and thawing, as this can have detrimental effects.
Storage bufferThis product is Rabbit IgG that has been prepared in phosphate buffered saline at pH 7.4. Additional components include 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This product should be stored at -20°C and is stable for up to 12 months from the date of receipt.

Target

Background

The removal of C-terminal basic residues (Arg or Lys) is specifically targeted towards peptides and proteins. This enzymatic process is thought to have significant involvement in regulating the activity of peptide hormones and growth factors at the cell surface. Additionally, it plays a crucial role in the localized degradation of extracellular proteins within the cell membrane. By selectively cleaving these basic residues, it exerts control over various biological processes and signaling pathways.

Celluar localizationExtracellular region or secreted;Plasma Membrane;
UniPortP14384


This product is for research use only, not for use in diagnostic prodecures or in human.


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