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Rabbit Anti-CKMT2 Polyclonal Antibody#abs133406

Rabbit Anti-CKMT2 Polyclonal Antibody#abs133406

Please note that the price mentioned above is for your reference only. For detailed pricing information, kindly reach out to our seller, Vecent. This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specificationDelivery timeUSD price

abs133406-100ug

1-2 Weeks

301.0

abs133406-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is for your reference only. For detailed pricing information, kindly reach out to our seller, Vecent.


Overview

catalog

abs133406
Other namesSarcomeric mitochondrial creatine kinase, also known as CKMT 2 or creatine kinase mitochondrial 2, is an essential enzyme located in the mitochondria that plays a significant role in cellular energy metabolism and muscle contraction. It is encoded by the CPK gene and is involved in the reversible transfer of phosphate between ATP and creatine. The enzyme is primarily found in the heart and skeletal muscles, where it catalyzes the conversion of creatine and ATP to phosphocreatine and ADP, providing energy for muscle contraction. CKMT 2 is an important biomarker for several pathological conditions, including heart failure and muscular dystrophy. Importantly, it is highly conserved across different species, indicating its critical role in cellular homeostasis.
SourceRabbit
SpecificityThe CKMT2 Antibody is capable of detecting total CKMT2 present within organisms. The levels of endogenous CKMT2 can be effectively detected using this antibody. By rearranging the original text, this statement is reiterated, highlighting the ability of this antibody to detect endogenous levels of total CKMT2 present within the organism.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesChicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
AntigenCKMT2
ApplicationFor Western blotting, a dilution of 1:500 to 1:1000 is recommended. For immunofluorescence or immunocytochemistry, a dilution range of 1:100 to 1:500 is suggested. For ELISA using peptides as antigens, a dilution of 1:20000 to 1:40000 is appropriate. It is important to note that these dilutions may require optimization for individual experiments.
ImmunogenA synthesized peptide.
MW48 KD
Properties

Concentration

1mg/ml

purificationSulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum.
ClonalityPolyclonal Antibody
Stability & StorageTo maintain the quality, keep the store at a temperature of -20 °C for a period of one year. Make sure to avoid subjecting the storage to multiple cycles of freezing and thawing.
Storage bufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Target

Background

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

Tissue specificitySarcomere-specific. Found only in heart and skeletal muscles.
Celluar localizationMitochondrion;
UniPortP17540

This product is for research use only, not for use in diagnostic prodecures or in human.


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