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Rabbit Anti-Choline Acetyltransferase Polyclonal Antibody#abs137221

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Description

Catalog-specification	Delivery time	USD price
abs137221-100ug	1-2 Weeks	301.0
abs137221-50ug	1-2 Weeks	201.0

Overview
catalog	abs137221
Other names	Choline O acetyltransferase, also known as ChAT, is an enzyme responsible for the synthesis of acetylcholine. This enzyme helps convert acetyl CoA and choline into acetylcholine, a neurotransmitter important for proper nervous system function. Other names for ChAT include acetyl CoA choline O acetyltransferase, CHOACTase, choline acetylase, choline O-acetyltransferase, and CMS1A. The ChAT gene is located on chromosome 10 and mutations in this gene can lead to congenital myasthenic syndromes. The EC number for ChAT is 2.3.1.6 and it is expressed in many tissues including the brain, spinal cord, and neuromuscular junction. Understanding ChAT function and regulation can aid in the development of treatments for neurological disorders.
Source	Rabbit
Specificity	The Choline Acetyltransferase Antibody is designed to recognize and measure the total levels of endogenous Choline Acetyltransferase in biological samples. Its specificity and sensitivity make it a reliable tool for researchers studying the role of Choline Acetyltransferase in various processes. By utilizing this antibody, researchers can obtain accurate and reproducible results that will aid in advancing their understanding of the function of Choline Acetyltransferase in the body.
Species Reactivity	Human
Antigen	Choline Acetyltransferase
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A newly developed peptide has been created using human Choline Acetyltransferase as its source. The peptide has been synthesized to closely mirror the structure and function of the original protein. This achievement marks a significant step forward in the field of biochemistry and has promising implications for potential therapeutic applications. Researchers are optimistic about the potential of this new peptide and are working to further explore its properties and potential benefits.
MW	83 kDa.
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin in peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to refrain from subjecting the product to multiple freeze/thaw cycles.
Storage buffer	The storage conditions for Rabbit IgG are as follows: It should be stored at -20 °C in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This solution is stable for a period of 12 months from the date of receipt.
Target
Background	Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
Celluar localization	Cytosol;Nucleus;
UniPort	P28329

Rabbit anti-Choline Acetyltransferase Polyclonal Antibody#abs137221

Western blot analysis Choline Acetyltransferase using HuvEc whole cell lysates

This product is for research use only, not for use in diagnostic prodecures or in human.

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