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Rabbit Anti-CFD Polyclonal Antibody#abs138931

Please note that the price provided is only for your reference. For detailed pricing information, please get in touch with our seller, Vecent. Western blot analysis CFD using K562 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs138931-100ug	1-2 Weeks	301.0
abs138931-50ug	1-2 Weeks	201.0

Please note that the price provided is only for your reference. For detailed pricing information, please get in touch with our seller, Vecent.

Overview
catalog	abs138931
Other names	Adipsin, also known as complement factor D, CFAD_HUMAN, CFD, or D component of complement, is an important protein that plays a crucial role in the complement system. This protein is also referred to as Adn or PFD. As a C3 convertase activator, Adipsin is responsible for the activation of the complement system which helps to remove foreign microbes and damaged cells from the body. Moreover, it serves as a properdin factor D by stabilizing the C3 convertase complex. The Adipsin protein is encoded by the CFD gene and is synthesized as a preproprotein. It is then cleaved into the mature form, which is a serine protease that belongs to the chymotrypsin family. Adipsin is widely distributed throughout the body and has been found to be expressed in a variety of tissues including adipose tissue, spleen, liver, and kidney. Dysfunction of the Adipsin protein has been implicated in various diseases such as obesity, diabetes, and cardiovascular diseases. In summary, Adipsin is an essential protein that is responsible for the proper functioning of the complement system, and its dysregulation can contribute to several pathological conditions.
Source	Rabbit
Specificity	The CFD Antibody is able to recognize levels of total CFD that are present naturally within the body. This detection method can provide valuable insight into the role of CFD in various physiological processes.
Species Reactivity	Human
Antigen	CFD
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CFD.
MW	27 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was accomplished through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure preservation, it is recommended to store the item at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the item to repeated freezing and thawing cycles.
Storage buffer	The storage conditions for Rabbit IgG include maintaining it in phosphate buffered saline with a pH of 7.4. It should be supplemented with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. The recommended storage temperature is -20 °C. This product is considered stable for a period of 12 months from the date it is received.
Target
Background	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
Celluar localization	Extracellular region or secreted;
UniPort	P00746