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Rabbit Anti-CEP27 Polyclonal Antibody#abs138881

Description

Catalog-specification	Delivery time	USD price
abs138881-100ug	1-2 Weeks	301.0
abs138881-50ug	1-2 Weeks	201.0

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Overview
catalog	abs138881
Other names	CEP27, also known as Centrosomal protein 27 kDa, is a key player in centrosome organization and function. This protein, encoded by the Chromosome 15 open reading frame 25 gene, is an essential component of the centrosome, a vital organelle that plays a pivotal role in cell division and spindle formation. CEP27 is a member of the HAUS augmentin-like complex, and functions as a subunit of the HAUS2 protein. Its involvement in the formation of complex protein structures that are essential for the proper functioning of centrosomes, underscores its importance as a regulator of cell division and organelle organization. The protein is highly conserved across species, with the human version being comprised of 216 amino acids. Its precise molecular function is not yet fully understood, but it is thought to play an important role in cell cycle progression, microtubule organization, and the regulation of spindle assembly checkpoint signaling. In summary, CEP27 is a critical protein that is essential for the proper organization and function of the centrosome, and as such it plays a vital role in the regulation of cell division. Its identification and further characterization will undoubtedly provide critical insights into a wide range of cellular processes and disease mechanisms.
Source	Rabbit
Specificity	The detection of endogenous levels of total CEP27 is made possible by the CEP27 Antibody. This antibody is designed to specifically identify and quantify the presence of CEP27 protein in biological samples. With its high specificity, scientists can accurately measure the amount of total CEP27 in various tissues and cell types. This vital information aids in studying the role and regulation of CEP27 in different biological processes. The CEP27 Antibody is a valuable tool for researchers aiming to gain a comprehensive understanding of CEP27's function and its potential implications in health and disease.
Species Reactivity	Human;Rat
Antigen	CEP27
Application	:WB 1:1000-3000，IHC 1:200，ELISA（）1:20000-1:40000。。。
Immunogen	A synthesized peptide derived from human CEP27.
MW	27 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To prevent damage, it is advised to store the item at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting it to multiple freeze and thaw cycles.
Storage buffer	The Rabbit IgG is stored in a solution of phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To maintain its stability, it should be stored at a temperature of -20 °C. This product will remain stable for a period of 12 months from the date it is received.
Target
Background	Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Celluar localization	Cytoskeleton;Cytosol;
UniPort	Q9NVX0