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Rabbit Anti-CDKL1 Polyclonal Antibody#abs133535

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Description

Catalog-specification	Delivery time	USD price
abs133535-100ug	1-2 Weeks	301.0
abs133535-50ug	1-2 Weeks	201.0

Overview
catalog	abs133535
Other names	CDC2-related kinase 1 (CDKL1), also known as cyclin-dependent kinase-like 1, is a serine/threonine protein kinase. It is encoded by the CDKL1 gene and is involved in cell cycle regulation. CDKL1 shares similarities with CDC2-related kinase and is often referred to as CDC2-related kinase 1. Other names for CDKL1 include CDK L1 and p42 protein kinase KKIALRE. CDKL1 belongs to the EC 2.7.11.22 enzyme class and plays a role in various cellular processes. Its function and activity are regulated by cyclins, similar to other cyclin-dependent kinases. CDKL1 is an important player in signal transduction pathways and is implicated in the regulation of cell proliferation and differentiation. Further research is needed to fully understand the precise mechanisms and physiological significance of CDKL1 in cellular processes.
Source	Rabbit
Specificity	Endogenous levels of total CDKL1 are recognized by the CDKL1 Antibody, indicating its ability to detect the native expression of CDKL1 protein. To reiterate, this antibody specifically targets and binds to total CDKL1 present within cells or tissues, allowing for its detection and analysis in experimental studies.
Species Reactivity	Human;Rat
Antigen	CDKL1
Application	The recommended dilution for Western blotting is between 1:500 and 1:1000, while for immunofluorescence or immunocytochemistry, it ranges from 1:100 to 1:500. For ELISA using peptide as the antigen, the suggested dilution is from 1:20000 to 1:40000. It is important to follow these dilution guidelines to ensure optimal results in your experiments.
Immunogen	A synthesized peptide.
MW	42 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography to purify the antiserum. This allowed for the isolation of a highly purified and specific product.
Clonality	Polyclonal Antibody
Stability & Storage	Please make sure to store it at -20 °C and avoid subjecting it to repeated freeze/thaw cycles for one year.
Storage buffer	The Rabbit IgG solution is suspended in a buffer of phosphate, saline, and sodium with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To maintain the solution's efficacy, it must be stored at a temperature of -20°C. The solution remains stable for up to 12 months from the date of purchase.
Target
Background	ATP + a protein = ADP + a phosphoprotein.
Tissue specificity	Highly expressed in kidney, and to a lower extent in ovary.
Celluar localization	Extracellular region or secreted;Nucleus;
UniPort	Q00532