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Rabbit Anti-CD81 Polyclonal Antibody#abs132701

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Description

Catalog-specification	Delivery time	USD price
abs132701-50ug	1-2 Weeks	201.0
abs132701-100ug	1-2 Weeks	301.0

Overview
catalog	abs132701
Description	The regulation of lymphoma cell growth is a crucial process that may be influenced by a certain protein. This protein is known to interact with a 16-kDa Leu-13 protein and together they form a complex that may be involved in signal transduction. Additionally, studies suggest that this protein may act as a viral receptor for HCV. Its role in these processes has yet to be fully elucidated, but its potential significance in lymphoma growth and viral infection makes it an area of active research.
Other names	TAPA1, also known as CD81, is a cell surface protein with a molecular weight of 26 kDa. It is an antigen targeted by the antiproliferative antibody 1. TAPA1, or CD81, belongs to the tetraspanin family and is encoded by the CD81 gene in humans. It is involved in various cellular processes and functions. TAPA1 is also referred to as TSPAN28 or S5.7 in some contexts. It plays a significant role in immune function and has been associated with Common Variable Immunodeficiency Disorder 6 (CVID6).
Source	Rabbit
Specificity	The CD81 antibody is capable of detecting total CD81 protein at its natural levels in the body. This indicates that the antibody can recognize and bind to the native CD81 protein present in biological samples.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Horse
Antigen	CD81
Application	，：WB 1:500-1:2000，IF/ICC 1:100-1:500，ELISA（）1:20000-1:40000。
Immunogen	A synthesized peptide.
MW	26 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. The resulting product is highly purified and free from unwanted contaminants, ensuring the highest quality of the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target
Background	May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.
Tissue specificity	Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
Posttranslational modification	Not glycosylated.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	P60033