Rabbit Anti-CD69 Polyclonal Antibody #abs130468

abs130468-50ug

1-2 Weeks

201

abs130468-100ug

1-2 Weeks

301

Description

The involvement of CD69 in lymphocyte proliferation is well-established, as it serves as a crucial receptor for signal transmission in lymphocytes, natural killer (NK) cells, and platelets. Its expression can be induced by various stimuli such as antigens, mitogens, or activators of protein kinase C (PKC) on the surface of both T and B-lymphocytes. Moreover, CD69 can also be triggered by the interaction of interleukin-2 (IL-2) with the p75 IL-2 receptor on NK cells. This intricate network of interactions highlights the significance of CD69 in regulating immune responses and cellular activities within the immune system.

Other names

The molecule known as activation inducer molecule (AIM/CD69) is also referred to as AIM, BL-AC/P26, BLAC/P26, C-type lectin domain family 2 member C, CD69 antigen (p60, early T-cell activation antigen), CD69 antigen, CD69 molecule, CD69_HUMAN, CLEC2C, EA1, early activation antigen CD69, early lymphocyte activation antigen, early T cell activation antigen p60, early T-cell activation antigen p60, GP32/28, Leu23, leukocyte surface antigen Leu-23, MLR-3, MLR3, VEA, and very early activation antigen. This molecule plays a crucial role in the early activation of T-cells. To generate a highly similar content, the following rearrangement can be made:
CD69, also known as activation inducer molecule (AIM/CD69), is an essential molecule in the early activation of T-cells. It is also referred to as AIM, BL-AC/P26, BLAC/P26, C-type lectin domain family 2 member C, CD69 antigen (p60, early T-cell activation antigen), CD69 antigen, CD69 molecule, CD69_HUMAN, CLEC2C, EA1, early activation antigen CD69, early lymphocyte activation antigen, early T cell activation antigen p60, early T-cell activation antigen p60, GP32/28, Leu23, leukocyte surface antigen Leu-23, MLR-3, MLR3, VEA, and very early activation antigen.

Source

Rabbit

Specificity

CD69 Antibody detects endogenous levels of CD69.

Species Reactivity

Human;Mouse;Rat

Application

（WB）1:500-1:2000，（IF/ICC）1:100-1:500，（ELISA）1:20000-1:40000（）。，。

Immunogen

A synthesized peptide derived from human CD69.

Properties

Concentration

1mg/ml

Purification

SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum.

Clonality

Polyclonal Antibody

Stability & Storage

To preserve the quality of the product, store it at a temperature of -20 °C for a period of one year. Extreme temperature changes should be avoided as much as possible to prevent any damage or deterioration of the product. Repeated freeze and thaw cycles should also be avoided. Take necessary precautions to ensure that the product remains in good condition throughout its shelf life.

Storage buffer

This content provides information on the storage conditions and stability of Rabbit IgG. The Rabbit IgG is dissolved in phosphate buffered saline at pH 7.4 and contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and remains stable for a period of 12 months from the date of receipt.

Target

Background

The receptor, found in lymphocytes, natural killer (NK) cells, and platelets, plays a crucial role in lymphocyte proliferation and functions as a signal transmitter.

Tissue specificity

This particular protein can be found on the outer layer of T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells, and platelets, especially when they are activated.

Posttranslational modification

Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.

Celluar localization

Plasma Membrane;

UniPort

Q07108