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Rabbit Anti-CD38 Polyclonal Antibody#abs136071

Sellers Vecent will provide you with the detailed price information. Please note that the price mentioned above is for reference purposes only. Feel free to contact Vecent for accurate pricing. Western blot analysis of extracts of mouse spleen, using CD38 antibody. This product is for research...

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Description

Catalog-specification	Delivery time	USD price
abs136071-50ug	1-2 Weeks	201.0
abs136071-100ug	1-2 Weeks	301.0

Sellers Vecent will provide you with the detailed price information. Please note that the price mentioned above is for reference purposes only. Feel free to contact Vecent for accurate pricing.

Overview
catalog	abs136071
Description	CD38 is found in numerous cells and tissues, predominantly leukocytes. This multifaceted ectoenzyme plays a crucial role in various cellular processes such as signal transduction, cell adhesion, and calcium signaling.
Other names	CD38 is an antigen found in acute lymphoblastic leukemia cells. It is also known as ADP ribosyl cyclase 1 and plays a crucial role in the synthesis of cyclic ADP-ribose, a molecule involved in calcium signaling. CD38 is a membrane-bound glycoprotein and is expressed in various tissues, including lymphocytes, muscle, and brain. It has also been identified as a potential target for cancer therapy due to its overexpression in certain types of cancer cells. Additionally, CD38 has been implicated in immune regulation and has been shown to influence the function of natural killer cells, T cells, and B cells. Overall, CD38 is a multifaceted protein with diverse roles in health and disease.
Source	Rabbit
Specificity	The presence of total CD38 can be effectively detected by the CD38 antibody, which specifically recognizes endogenous levels of the protein.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit
Antigen	CD38
Application	The recommended dilutions for WB range from 1:500 to 1:2000. For IHC, the suggested dilutions are between 1:50 to 1:200, while for IF/ICC, the range is 1:100 to 1:500. In the case of ELISA using peptide, it is advised to dilute at 1:20000 to 1:40000.
Immunogen	A synthesized peptide derived from human CD38.
MW	34kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was conducted through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 Â°C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 Â°C.Stable for 12 months from date of receipt.
Target
Background	Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Tissue specificity	Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Celluar localization	Extracellular region or secreted;Nucleus;Plasma Membrane;
UniPort	P28907