Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-CD180 Polyclonal Antibody#abs132691

Please note that the price provided is only for your reference. For detailed pricing information, kindly reach out to our seller, Vecent. In order to ensure accuracy, it is important to communicate directly with Vecent for specific pricing details. Western blot analysis of CD180 expression in...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs132691-100ug	1-2 Weeks	301.0
abs132691-50ug	1-2 Weeks	201.0

Overview
catalog	abs132691
Description	In B-cells, it is possible to collaborate with MD-1 and TLR4 to trigger the innate immune response to bacterial lipopolysaccharide (LPS). This activation results in the activation of NF-kappa-B. Furthermore, it has been demonstrated to play a part in the B-cell life/death decision.
Other names	CD180, also known as Ly78 or lymphocyte antigen 64, is an antigen that plays a role in radioprotection. It is a 105 kDa protein that is expressed on lymphocytes and other immune cells. The gene encoding CD180 is designated F630107B15 and is also known as MGC126233 and MGC126234. CD180 is important in the immune response and is a potential target for therapeutic intervention in certain diseases. Another name for CD180 is RP105, which stands for radioprotective 105 kDa protein. Overall, CD180 is an important antigen that is involved in protecting cells from radiation damage and has potential applications in medicine.
Source	Rabbit
Specificity	The CD180 antibody is capable of detecting the complete amount of CD180 present within the organism. This means that it is able to identify and isolate the natural levels of CD180 without any external interference or factors. The detection process is highly accurate and reliable, ensuring that researchers and scientists can obtain valuable insights into the behavior and function of CD180 within the body.
Species Reactivity	Human
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	CD180
Application	For Western Blot, the recommended dilution range is between 1:500 to 1:2000. When it comes to Immunohistochemistry, the advised dilution range is between 1:50 to 1:200. For ELISA assays using peptides, the dilution range of 1:20000 to 1:40000 is highly recommended. It is imperative to note that dilution ranges ought to be optimized based on the specific experiments or assays being conducted. Thus, researchers should perform preliminary experiments to determine the ideal dilution range for their particular application.
Immunogen	A synthesized peptide.
MW	90 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated freezing and thawing cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target
Background	May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity).
Tissue specificity	Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
Celluar localization	Plasma Membrane;
UniPort	Q99467