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Rabbit Anti-CCR9 Polyclonal Antibody#abs133249

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Description

Catalog-specification	Delivery time	USD price
abs133249-100ug	1-2 Weeks	301.0
abs133249-50ug	1-2 Weeks	201.0

Overview
catalog	abs133249
Other names	CCR9, also known as CC chemokine receptor type 9 or CDw199, is a chemokine receptor belonging to the C-C motif chemokine receptor family. It is also referred to as CCBP2, CCCKR9, or CCR10. GPR28 or GPR96 is another name for this receptor. This receptor plays a crucial role in immune cell trafficking and migration. Furthermore, it is involved in the recruitment of leukocytes to inflamed tissues. CCR9 is encoded by the CCR9 gene and exists in multiple isoforms. One isoform is known as CRA_a, while others are labeled isoform A and isoform B. Along with chemokine CCL25, CCR9 is responsible for the homing of specific immune cells to the gut mucosa. Additionally, the chemokine-binding protein D6 is associated with CCR9. OTTHUMP00000164653 and OTTHUMP00000164654 are also alternative identifiers for this chemokine receptor. As such, CCR9 serves as an essential component in various immune responses and represents a potential therapeutic target for immune-related disorders and diseases.
Source	Rabbit
Specificity	Endogenous levels of total CCR9 can be detected using the CCR9 Antibody. The antibody has been designed to specifically recognize and bind to CCR9, allowing for precise detection of this protein. This high-quality antibody is a reliable tool for investigating the role of CCR9 in various biological processes and disease states. By detecting endogenous levels of CCR9, researchers can gain valuable insights into the function and regulation of this important protein.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Sheep;Rabbit;Horse;Pig;
Antigen	CCR9
Application	For WB, the recommended dilution ranges from 1:1000 to 1:3000, while for ICC, it is 1:100 to 1:500. For ELISA using peptides, a dilution of 1:20000 to 1:40000 is recommended. It is important to follow these dilution guidelines in order to obtain accurate and reliable results.
Immunogen	A synthesized peptide derived from human CCR9.
MW	45kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed for peptide affinity chromatography in order to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.
Tissue specificity	Highly expressed in the thymus and low in lymph nodes and spleen.
Celluar localization	Plasma Membrane;
UniPort	P51686