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Rabbit Anti-CATSPER3 Polyclonal Antibody#abs138870

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Description

Catalog-specification	Delivery time	USD price
abs138870-100ug	1-2 Weeks	301.0
abs138870-50ug	1-2 Weeks	201.0

Overview
catalog	abs138870
Other names	The Ca(v)-like protein, also known as CACRC or calcium channel repeat containing 1, is a putative ion channel that is crucial for male fertility. This protein is also referred to as Cation channel sperm-associated protein 3 or CatSper3, as it is primarily expressed in sperm cells and plays a crucial role in sperm motility and fertilization. The Cation channel, sperm associated 3 has a unique structure, consisting of one-repeat calcium channel-like protein that is composed of multiple transmembrane segments. Recent studies have suggested that CatSper3 plays a crucial role in facilitating the entry of calcium ions into sperm cells, a process that is essential for proper sperm motility and successful fertilization. Overall, the importance of CatSper3 in male fertility cannot be overstated, and ongoing research is aimed at further elucidating its precise role in the complex process of fertilization.
Source	Rabbit
Specificity	The CATSPER3 Antibody has the capability to recognize the endogenous levels of total CATSPER3 without any external intervention. The content generated from this information will be closely similar but arranged in a different pattern.
Species Reactivity	Human
Antigen	CATSPER3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CATSPER3.
MW	46 kDa
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, peptide affinity chromatography was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimum storage conditions, it is recommended to keep the product at a temperature of -20 °C for up to one year. It is important to avoid any instances of repeated freeze/thaw cycles as this could result in a change in the product's properties and quality.
Storage buffer	This rabbit IgG solution is suspended in a pH 7.4 phosphate buffered saline with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this solution at -20 °C, and it remains stable for up to 12 months from the date of receipt.
Target
Background	Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
Tissue specificity	Testis-specific.
Celluar localization	Endoplasmic reticulum;Plasma Membrane;
UniPort	Q86XQ3