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Rabbit Anti-Cathelicidin Polyclonal Antibody#abs137218

Description

Catalog-specification	Delivery time	USD price
abs137218-100ug	1-2 Weeks	301.0
abs137218-50ug	1-2 Weeks	201.0

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Overview
catalog	abs137218
Other names	The 18 kDa cationic antimicrobial protein, also known as CAP18 or cathelicidin antimicrobial peptide, is a type of antibacterial protein that plays an important role in the body's immune defense against microbial infections. It is produced by various types of cells in the body, including white blood cells and epithelial cells, and has been found in a variety of species, including all mammals. The protein has several different names, such as FALL-39, MCLP, and CLP, but they all refer to the same protein and its biological function. This protein is known for its potent antibacterial activity against a wide range of microbial pathogens and is important for fighting infections in the body. Its ability to kill bacteria lies in its cationic and amphipathic structure, which allows it to penetrate and disrupt the bacterial cell membrane. Research has shown that this protein may have potential therapeutic applications in the treatment of infectious diseases, as well as in wound healing and tissue repair.
Source	Rabbit
Specificity	Total endogenous levels of Cathelicidin can be detected by using the Cathelicidin Antibody.
Species Reactivity	Human;Mouse;Rat
Antigen	Cathelicidin
Application	The recommended dilutions for the use of this antibody are as follows: 1:1000-3000 for western blot analysis, 1:200 for immunohistochemistry, and 1:20000-1:40000 for ELISA analyses with peptide. It is important to use the appropriate dilution for each technique to obtain accurate results. The dilution range for western blot analysis is relatively broad compared to that for immunohistochemistry and ELISA. When using this antibody, it is also advisable to follow the manufacturer's instructions and appropriate protocols for the best performance. Ensure that the concentrations of the sample and primary antibody are optimized for the intended application to obtain reliable and consistent results.
Immunogen	CathelicidinCathelicidin。，。
MW	19 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the process of peptide affinity chromatography was employed to purify the antiserum. To achieve this, the resin was coupled with peptides to allow for selective binding of the antiserum, resulting in a highly purified final product.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product for an extended period, keep it stored at a temperature of -20 °C. It is advisable to refrain from subjecting it to multiple freeze/thaw cycles as this could adversely affect its integrity. This storage condition should be maintained for up to one year.
Storage buffer	The recommended storage condition for Rabbit IgG is at -20 °C in a solution containing phosphate buffered saline at pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures the stability of the product for a period of 12 months from the date of receipt.
Target
Background	Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
Tissue specificity	Expressed in bone marrow and testis and neutrophils.
Posttranslational modification	The N-terminus is blocked.
Celluar localization	Extracellular region or secreted;
UniPort	P49913