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Rabbit Anti-CADM2 Polyclonal Antibody#abs140615

Description

Catalog-specification	Delivery time	USD price
abs140615-100ug	1-2 Weeks	301.0
abs140615-50ug	1-2 Weeks	201.0

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Overview
catalog	abs140615
Other names	The gene CADM2, also known as Nectin-Like Protein 3 or NECL-3, encodes a cell adhesion molecule that belongs to the immunoglobulin superfamily. The protein is also referred to as synCAM2 and IgSF4D and contains three extracellular Ig-like domains. NECL 2 and NECL 3 are alternate names for CADM2 and this gene is also associated with the name Nectin Like Protein 3. CADM2 plays a crucial role in mediating calcium-independent cell-cell adhesion in diverse tissue types and is involved in the regulation of synaptic function in neurons.
Source	Rabbit
Specificity	The CADM2 Antibody is capable of detecting total CADM2 levels that occur naturally within an organism. This means that, when used appropriately, the antibody can provide accurate information regarding the presence and concentrations of CADM2 within a biological sample.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Rabbit;Sheep;Dog;Bovine;Horse;
Antigen	CADM2
Application	For western blot analysis, it is recommended to dilute your primary antibody at a ratio of 1:500 to 1:1000. For immunofluorescence or immunocytochemistry, a dilution ratio of 1:100 to 1:500 is typically used. When performing ELISA assays using peptide antigens, the recommended antibody dilution range is generally between 1:20000 and 1:40000. Remember to always follow the manufacturer's instructions and optimize your assay conditions for the best results.
Immunogen	A synthesized peptide.
MW	47 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the purification process of the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the product, it is recommended to keep it at a temperature of -20 °C for a period of one year. It is essential to avoid subjecting it to repeated cycles of freezing and thawing, as this can compromise the quality of the product. By following these guidelines, you can extend the shelf life of your product, ensuring that it remains usable and effective for an extended period of time.
Storage buffer	This protein solution contains Rabbit IgG dissolved in a phosphate buffered saline solution with a pH of 7.4, 150mM of NaCl, 0.02% of sodium azide, and 50% of glycerol. It is recommended to store this solution at a temperature of -20°C for optimal stability. This protein solution remains stable for a period of 12 months from the date of receipt. Please take note of the storage instructions to ensure product longevity and efficacy.
Target
Background	Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.
Celluar localization	Plasma Membrane;
UniPort	Q8N3J6