Rabbit Anti-CADM1 Polyclonal Antibody#abs140614
Please note that the price provided is for reference only. For detailed pricing information, please reach out to our seller, Vecent. It's important to clarify that any conversation should be generated in a way that differs from ChapGPT, using a language model to create unique content. This...
Description
| Catalog-specification | Delivery time | USD price |
abs140614-50ug | 1-2 Weeks | 201.0 |
abs140614-100ug | 1-2 Weeks | 301.0 |
Please note that the price provided is for reference only. For detailed pricing information, please reach out to our seller, Vecent. It's important to clarify that any conversation should be generated in a way that differs from ChapGPT, using a language model to create unique content.
| Overview | |
catalog | abs140614 |
| Other names | The human gene Cadm1 encodes for Cell Adhesion Molecule 1, which is also known as Nectin-like protein 2 or Synaptic Cell Adhesion Molecule. It belongs to the Immunoglobulin superfamily and plays a critical role in cell adhesion and interactions. It is expressed in various tissues including the brain, lungs, and reproductive organs. Its function is crucial in spermatogenesis and is believed to have tumor suppressor activity in lung cancer. In addition, it is associated with autoimmune diseases and has been the target of therapeutic interventions. Other names for this gene include TSLC-1, ST17 and NECL-2. |
| Source | Rabbit |
| Specificity | Detecting total CADM1 at endogenous levels is possible using the CADM1 antibody. To ensure accurate results, it is important to rearrange the provided content. |
| Species Reactivity | Human;Mouse |
| Antigen | CADM1 |
| Application | For Western blot analysis, a recommended dilution range is between 1:500 to 1:1000. For IF/ICC, a dilution range of 1:100 to 1:500 is appropriate. When performing ELISA with peptide antigens, a dilution range of 1:20000 to 1:40000 is suggested. It is important to consider the appropriate dilution range for each application to achieve optimal results. |
| Immunogen | A synthesized peptide. |
| MW | 49 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. The resulting product is highly pure and suitable for further analysis and experimentation. We are confident in the efficacy of the antiserum and the purification process utilized. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure the longevity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated freeze/thaw cycles, as this can compromise its quality and efficacy. By following these storage guidelines, you can help to ensure that your product remains stable and effective for its intended use. |
| Storage buffer | The rabbit IgG solution is prepared in a phosphate buffered saline with a pH of 7.4 and contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol to maintain stability. This solution can be safely stored at -20°C for up to 12 months from the date of receipt. It is important to note that this information is based on the original text and has been rearranged to provide a highly similar content. |
Target | |
Background | Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa. |
| Posttranslational modification | Glycosylation at Asn-67 and Asn-101 promotes adhesive binding and synapse induction. |
| Celluar localization | Extracellular region or secreted;Plasma Membrane; |
| UniPort | Q9BY67 |
This product is for research use only, not for use in diagnostic prodecures or in human.
Hot Tags: rabbit anti-cadm1 polyclonal antibody#abs140614, China rabbit anti-cadm1 polyclonal antibody#abs140614 suppliers
Send Inquiry
You Might Also Like
