Rabbit Anti-Casein Kinase2 Beta Polyclonal Antibody#abs137043

Rabbit Anti-Casein Kinase2 Beta Polyclonal Antibody#abs137043

Please note that the price mentioned above is only for your reference. For more detailed pricing information, please get in touch with our sales representative, Vecent. Western blot analysis Casein Kinase 2 beta using HeLa whole cell lysates This product is for research use only, not for use in...

Description

Catalog-specificationDelivery timeUSD price

abs137043-100ug

1-2 Weeks

301.0

abs137043-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is only for your reference. For more detailed pricing information, please get in touch with our sales representative, Vecent.


Overview

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abs137043
Other namesThe Casein kinase 2 beta polypeptide, also known as Casein kinase II beta subunit or CK II beta, is an important protein in the human body. This protein is a subunit of the CK2 enzyme, which is involved in many cellular processes such as cell growth, differentiation, and apoptosis. The CSK2B gene codes for the production of the CK2 beta subunit, which is essential for proper functioning of the CK2 enzyme.
In addition to its role in regulating cellular processes, the CK2 beta subunit has also been implicated in certain diseases such as cancer and neurodegenerative disorders. Therefore, understanding the structure and function of this protein is crucial for developing new therapies for these conditions.
The CK2 beta subunit is composed of 215 amino acids and is highly conserved across different species. It interacts with other proteins such as the CK2 alpha subunit to form the active enzyme complex. Studies have shown that the CK2 beta subunit plays a crucial role in regulating the activity of the CK2 enzyme and stabilizing its structure.
Overall, the CK2 beta subunit is a multifunctional protein that is critical for many biological processes in the human body. Further research into the structure and function of this protein could reveal new insights into its role in health and disease.
SourceRabbit
SpecificityEndogenous levels of total Casein Kinase 2 beta can be detected using the Casein Kinase 2 beta Antibody. This antibody specifically targets and identifies the presence of Casein Kinase 2 beta in biological samples. By utilizing this antibody, researchers can accurately assess the amount of Casein Kinase 2 beta present in a given sample, allowing for further investigation into its role and function. The detection of endogenous Casein Kinase 2 beta levels using this antibody is a valuable tool for studying various biological processes and pathways.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesZebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
AntigenCasein Kinase2 β
ApplicationHere's an alternative version of the same content:
When using this antibody for Western blotting, dilute it at a ratio of 1:1000-3000. For immunohistochemistry, use a dilution of 1:200. If you're performing immunofluorescence or immunocytochemistry, you'll want to dilute the antibody at a ratio of 1:100-1:500. Lastly, if you're using the antibody in an ELISA experiment with peptide, you should dilute it at a ratio of 1:20000-1:40000. By using appropriate dilutions, you can ensure accurate and reliable results in your experiments.
ImmunogenThe human Casein Kinase 2 beta has been utilized to synthesize a peptide with impressive similarity. This synthesized peptide was meticulously derived from the aforementioned protein, ensuring that its origin lies in human Casein Kinase 2 beta. The process of rearranging the original content led to the creation of a peptide that closely resembles its precursor, thus maintaining the basis of the original text information.
MW25 kDa
Properties

Concentration

1mg/ml

purificationUsing SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography purification. It was purified to ensure optimal effectiveness in its intended use.
ClonalityPolyclonal Antibody
Stability & StorageTo maintain its shelf life for up to a year, it is recommended to store the product at a temperature of -20 °C. To prevent any potential damage from repeated freeze/thaw cycles, it is advised to avoid subjecting the product to such cycles.
Storage bufferThis product contains Rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. To maintain optimal performance, it is recommended that this product be stored at -20°C. This product is stable for up to 12 months from the date of receipt.

Target

Background

Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.

Posttranslational modificationPhosphorylated by alpha subunit.
Celluar localizationCytosol;Extracellular region or secreted;Nucleus;Plasma Membrane;
UniPortP67870


Western blot analysis Casein Kinase 2 beta using HeLa whole cell lysates


This product is for research use only, not for use in diagnostic prodecures or in human.


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