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Rabbit Anti-CAMP Polyclonal Antibody#abs136043

Description

Catalog-specification	Delivery time	USD price
abs136043-100ug	1-2 Weeks	301.0
abs136043-50ug	1-2 Weeks	201.0

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Overview
catalog	abs136043
Description	This antimicrobial peptide family member is encoded by a gene that features a cathelin domain within its highly conserved N-terminal signal peptide. The cationic antimicrobial peptide is structurally variable and is produced through extracellular proteolysis from the C-terminus. Besides its antimicrobial activity, the encoded protein also has additional functions such as cell chemotaxis, regulation of the inflammatory response, and induction of immune mediators. These functions highlight the protein's versatility and importance in maintaining the body's ability to defend itself against pathogens. This information was provided by RefSeq in August 2011.
Other names	The 18 kDa cationic antimicrobial protein, also known as CAP-18, is a cathelin-like protein that produces the cathelicidin antimicrobial peptide. This peptide, also referred to as LL-37, has significant antibacterial properties and is also capable of combating a wide range of other pathogens. Additionally, the protein FALL-39 is an antibacterial peptide that also possesses antimicrobial activity. Both of these peptides, along with the CATHL3 protein, are classified as cationic antimicrobial proteins and play significant roles in host defense. Other related peptides include CLP and Cnlp, while CRAMP is the mouse homolog of FALL-39. PR-39 is the porcine homolog of FALL-39. Overall, these cationic antimicrobial proteins and related peptides play crucial roles in combating infections and supporting the immune system.
Source	Rabbit
Specificity	The endogenous levels of total CAMP are detected by the CAMP Antibody.
Species Reactivity	Human;Mouse
Antigen	CAMP
Application	The dilution factors for Western Blot (WB) range from 1:500 to 1:2000, for Immunohistochemistry (IHC) they range from 1:50 to 1:200, and for ELISA (peptide) they range from 1:20000 to 1:40000. It is important to note that these dilution ranges are based on the original text information provided.
Immunogen	A synthesized peptide derived from human CAMP.
MW	19kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to conduct peptide affinity chromatography and purify the antiserum. Please rearrange the provided information in a manner similar to the original text.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 Â°C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 Â°C.Stable for 12 months from date of receipt.
Target
Background	Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
Tissue specificity	Expressed in bone marrow and testis and neutrophils.
Posttranslational modification	The N-terminus is blocked.
Celluar localization	Extracellular region or secreted;
UniPort	P49913