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Rabbit Anti-CALML3 Polyclonal Antibody#abs138835

Description

Catalog-specification	Delivery time	USD price
abs138835-100ug	1-2 Weeks	301.0
abs138835-50ug	1-2 Weeks	201.0

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Overview
catalog	abs138835
Other names	Calmodulin-like 3, also known as Calmodulin-related protein NB-1 or CaM-like protein, is a protein encoded by the CALML3 gene. It plays a crucial role in calcium signaling and modulation of various cellular processes. The OTTHUMP00000019004 gene is responsible for the production of this protein. With its similarity to calmodulin, Calmodulin-like 3 is involved in regulating the activity of several enzymes and ion channels. This protein is expressed in various tissues and is particularly abundant in the brain, heart, and skeletal muscle. The unique characteristics of Calmodulin-like 3 make it an interesting target for further research in the field of molecular biology and biomedical sciences.
Source	Rabbit
Specificity	Endogenous levels of total CALML3 can be detected with the CALML3 antibody. This antibody is highly sensitive and specific in detecting CALML3 in various samples. By using this antibody, researchers can easily analyze the expression of CALML3 in different tissues and cells. The detection of CALML3 can provide important insights into the molecular pathways that are regulated by this protein, which is crucial in several physiological and pathological processes. Overall, the CALML3 antibody is a valuable tool for investigating the function and regulation of CALML3 in biological systems.
Species Reactivity	Human;Mouse;Rat
Antigen	CALML3
Application	The recommended dilutions for Western blotting range between 1:1000-3000, while for immunohistochemistry the dilution should be 1:200. For ELISA assays using peptides, a dilution of 1:20000-1:40000 is recommended for optimal results. It is important to follow these dilution guidelines to ensure accurate and reliable results in your experiments.
Immunogen	A synthesized peptide derived from human CALML3.
MW	17 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimal storage, it is recommended to store at a temperature of -20 °C for a period of one year. It is advised to avoid subjecting the product to multiple freeze/thaw cycles as it can have a negative impact on the quality of the product. It is important to follow these guidelines to ensure the longevity and effectiveness of the product.
Storage buffer	The provided content outlines the storage and stability conditions for Rabbit IgG in phosphate buffered saline (PBS), pH 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. According to the information, it is recommended to store the solution at -20 °C. The stability period of Rabbit IgG is stated as 12 months starting from the date of receipt.
Target
Background	May function as a specific light chain of unconventional myosin-10 (MYO10), also enhances MYO10 translation, possibly by acting as a chaperone for the emerging MYO10 heavy chain protein. May compete with calmodulin by binding, with different affinities, to cellular substrates.
Tissue specificity	Expressed in normal mammary, prostate, cervical, and epidermal tissues. It is greatly reduced or undetectable in transformed cells.
Celluar localization	Extracellular region or secreted;
UniPort	P27482