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Rabbit Anti-BRI3 Polyclonal Antibody#abs138804

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Description

Catalog-specification	Delivery time	USD price
abs138804-100ug	1-2 Weeks	301.0
abs138804-50ug	1-2 Weeks	201.0

Overview
catalog	abs138804
Other names	Brain protein I3; BRI3; BRI3_HUMAN; I3; pRGR2;
Source	Rabbit
Specificity	The detection of total BRI3 at endogenous levels can be achieved through the use of the BRI3 Antibody. This antibody specifically targets BRI3 and identifies all forms of the protein present within a sample. By detecting the total levels of BRI3, researchers can gain insight into its expression and function within a biological system.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Bovine;Dog
Antigen	BRI3
Application	The recommended dilution for WB is between 1:1000 to 3000, for IHC it is 1:200, and for ELISA using peptide it is between 1:20000 to 1:40000. These dilutions ensure the best results for each application and can be adjusted depending on the specific experimental conditions. It is important to follow the recommended dilutions to avoid non-specific binding and false positive results.
Immunogen	A synthesized peptide derived from human BRI3.
MW	14 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. A highly effective method, this procedure was employed to achieve optimal purification of the substance.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimal storage conditions, it is recommended to store the item at a temperature of -20°C for up to a year. It is important to avoid subjecting the product to multiple rounds of freezing and thawing, as this can have a negative impact on its quality. Make sure to follow these guidelines to preserve the item's integrity.
Storage buffer	The recommended storage conditions for Rabbit IgG include keeping it in phosphate buffered saline (pH 7.4) containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is advised to store it at a temperature of -20 °C. This storage condition ensures stability for a period of 12 months starting from the date of receipt. Please note that the information provided is based on the original text and rearranged to generate a highly similar content.
Target
Background	Participates in tumor necrosis factor-alpha (TNF)-induced cell death (PubMed:14592447). May be a target of Wnt/beta-catenin signaling in the liver (PubMed:20538055).
Tissue specificity	Up-regulated during TNF-mediated inflammation and immunity (By similarity). Up-regulated by beta-catenin and TCF4 (PubMed:20538055).
Celluar localization	Lysosome;Plasma Membrane;
UniPort	O95415