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Rabbit Anti-BEGAIN Polyclonal Antibody#abs140378

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Description

Catalog-specification	Delivery time	USD price
abs140378-100ug	1-2 Weeks	301.0
abs140378-50ug	1-2 Weeks	201.0

Overview
catalog	abs140378
Other names	Guanylate kinase-associated protein, also known as brain-enriched guanylate kinase-associated homolog (in rats) or KIAA1446, is a protein that is highly abundant in the brain. It is associated with the SAP90/PSD95 protein family and plays a crucial role in synaptic function. This protein, often referred to as SAPAP or SAP90/PSD95 Associated Proteins, is involved in the regulation of neuronal signaling and synaptic plasticity. It is believed to participate in the organization and stabilization of synaptic structures, as well as the modulation of neurotransmitter receptors. The exact function of brain-enriched guanylate kinase-associated protein is still being studied, but it is thought to be important for proper brain development and function. Research has shown that mutations or dysregulation of this protein can lead to cognitive impairment and various neurological disorders. Brain-enriched guanylate kinase-associated protein has garnered significant attention in the scientific community, and further research is being conducted to fully understand its role in brain function and its potential as a therapeutic target for neurological disorders. As our understanding of this protein continues to grow, it may pave the way for the development of novel treatments for brain-related conditions.
Source	Rabbit
Specificity	The total endogenous levels of BEGAIN can be detected using the BEGAIN Antibody.
Species Reactivity	Human
Predictive reaction species	Horse;Dog;
Antigen	BEGAIN
Application	WB 1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human BEGAIN.
MW	65kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. To obtain a highly pure form of the antiserum, this method was employed.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure prolonged shelf life, it is recommended to store at a temperature below -20°C for up to one year. It is important to avoid repeated instances of freezing and thawing as this can affect the quality of the product.
Storage buffer	The recommended storage condition for Rabbit IgG is at -20 °C in phosphate buffered saline (pH 7.4) containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This antibody is stable for 12 months from the date of receipt.
Target
Background	May sustain the structure of the postsynaptic density (PSD).
UniPort	Q9BUH8