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Rabbit Anti-AZGP1 Polyclonal Antibody#abs136816

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Description

Catalog-specification	Delivery time	USD price
abs136816-100ug	1-2 Weeks	301.0
abs136816-50ug	1-2 Weeks	201.0

Overview
catalog	abs136816
Description	Zinc-alpha-2-glycoprotein (AZGP1) is a protein that can be found in body fluids and is responsible for mobilizing lipids. It is typically expressed in the secretory epithelia of various organs, such as the liver, lungs, breast, GI tract, and sweat glands. AZGP1 shares a lot of structural similarities with the class I major histocompatibility complex (MHC) antigens. AZGP1 is known for its role in carcinogenesis and differentiation. The expression of AZGP1 can be altered in various cancer types, including breast cancer, prostate cancer, lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma, and oral tumors. Several studies have shown the importance of AZGP1 in the progression and development of these cancer types.
Other names	Zinc-alpha-2-glycoprotein (ZAG) is also known as Alpha 2 glycoprotein 1 zinc or Alpha 2 glycoprotein zinc binding. It is a protein that binds to zinc and plays a role in regulating lipid metabolism and glucose homeostasis. The precursor form of ZAG is known as Zinc alpha 2 glycoprotein precursor. Other names for this protein include Azgp1, ZA2G, ZA2G_HUMAN, Zn alpha 2 glycoprotein, Zn alpha 2 GP, Zn alpha2 glycoprotein, Zn-alpha-2-GP, and ZNGP1. ZAG is an important biomarker for certain diseases such as cancer and diabetes, and it is currently being studied for its potential therapeutic uses. In summary, Zinc-alpha-2-glycoprotein is a multifaceted protein that has important roles in our bodies, and its functions are still being explored by scientists.
Source	Rabbit
Specificity	The AZGP1 Antibody has the ability to identify the complete amount of endogenous AZGP1 protein. We can create a corresponding content that is based on this information by rephrasing and rearranging some of the words and phrases in the original text.
Species Reactivity	Human;Mouse
Antigen	AZGP1
Application	The dilution factors for WB, IHC, and ELISA (peptide) are as follows: WB is diluted at a ratio of 1:500 to 1:2000, IHC is diluted at a ratio of 1:50 to 1:200, and ELISA (peptide) is diluted at a ratio of 1:20000 to 1:40000. These dilutions are important for optimal performance and accuracy of the respective assays.
Immunogen	A synthesized peptide derived from human AZGP1.
MW	34kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography purification. The resulting purified antiserum exhibits high similarity to the original source material.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids.
Tissue specificity	Blood plasma, seminal plasma, urine, saliva, sweat, epithelial cells of various human glands, liver.
Posttranslational modification	N-glycosylated. N-glycan at Asn-128: Hex5HexNAc4.
Celluar localization	Extracellular region or secreted;Nucleus;Plasma Membrane;
UniPort	P25311