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Rabbit Anti-ANAPC5 Polyclonal Antibody#abs135033

Please note that the price provided is only for your reference. For more detailed pricing information, we kindly ask you to contact our seller, Vecent. Thank you. This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs135033-100ug	1-2 Weeks	301.0
abs135033-50ug	1-2 Weeks	201.0

Please note that the price provided is only for your reference. For more detailed pricing information, we kindly ask you to contact our seller, Vecent. Thank you.

Overview
catalog	abs135033
Other names	The gene 2510006G12Rik, also known as AA408751, AA536819, AA986414, ANAPC 5, Anaphase promoting complex subunit 5, or simply APC5, is a vital component of the anaphase-promoting complex. This protein, also referred to as Cyclosome subunit 5 or PDL 108, plays a crucial role in the orderly progression of cell division by helping to regulate the timing of protein degradation. Additionally, APC5 is involved in various cellular processes, including the maintenance of genomic stability and the prevention of chromosomal instability. It is also known as RMC1 and Periodontal ligament fibroblast protein. Overall, APC5 is an essential component of cellular machinery that helps ensure the accurate and efficient separation of chromosomes during cell division.
Source	Rabbit
Specificity	The ANAPC5 Antibody is specifically designed to detect total ANAPC5 levels in the body. It accurately identifies the endogenous levels of ANAPC5, providing reliable and accurate results. To maintain the consistency of the original content, rearranging the information has been done while keeping its essence intact.
Species Reactivity	Human
Antigen	ANAPC5
Application	For Western blotting, a dilution range of 1:500 to 1:1000 is recommended. When using immunofluorescence or immunocytochemistry techniques, a dilution ratio of 1:100 to 1:500 is suggested. For ELISA assays using peptides, a dilution range of 1:20000 to 1:40000 is suitable. It is important to maintain proper dilutions to ensure accurate results in all experiments.
Immunogen	A synthesized peptide.
MW	85 KD
Properties
Concentration	1mg/ml
purification	The purification process for the antiserum involved using SulfoLink™ Coupling Resin and peptide affinity chromatography. The aim was to create a highly purified end product. Using this method ensures that the antiserum is of the best quality and can be used effectively for various purposes. The process involved careful monitoring to ensure that all impurities are removed, resulting in a highly effective final product. Overall, peptide affinity chromatography using SulfoLink™ Coupling Resin is an effective method for purifying antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	The recommended storage condition for this product is at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting the product to multiple freeze/thaw cycles.
Storage buffer	The Rabbit IgG is stored in phosphate buffered saline, which has a pH 7.4, 150mM NaCl, and 0.02% sodium azide. It is also preserved with 50% glycerol and should be kept at a temperature of -20 °C. This product has a shelf life of 12 months from the date of receipt, making it a reliable and long-lasting choice for your research needs. Ensure that you follow proper storage protocols to maintain product stability and efficacy.
Target
Background	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Celluar localization	Cytosol;Nucleus;
UniPort	Q9UJX4